Results 11 to 20 of about 23 (23)
Cancer Science, EarlyView.ABSTRACT In the randomized phase III CheckMate 77T study, perioperative nivolumab showed statistically significant and clinically meaningful improvement in event‐free survival (EFS) vs. placebo in patients with resectable, non‐metastatic non‐small cell lung cancer (NSCLC).
Fumihiro Tanaka +17 more
wiley +1 more source
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Contact Dermatitis, EarlyView.Allergic contact dermatitis is very common in patients with anogenital lesions referred for patch testing in Spain. Key allergens include fragrances, preservatives and topical treatments like anaesthetics and steroids. Emerging sensitisers including benzisothiazolinone and sodium metabisulphite are also relevant.
Mercè Grau‐Pérez +29 more
wiley +1 more source
Pediatric Dermatology, EarlyView.ABSTRACT Background/Objective Growing evidence highlights the role of physiological lipids, namely ceramides, cholesterol, and free fatty acids, in maintaining skin barrier function and preventing atopic dermatitis (AD). Current evidence on the efficacy, safety, and clinical relevance of stratum corneum (SC) lipid‐based therapies to prevent AD and ...
Chon‐Wai Jeremy Chan +1 more
wiley +1 more source
Is There a Topical Nasal Steroid Spray That Works the Best for Nasal Congestion?
The Laryngoscope, EarlyView.
Benjamin Aunins +3 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.ABSTRACT Model‐based meta‐analysis allows integration of aggregated‐level data (AD) from different clinical trials in one model to assess population efficacy/safety. However, AD is limited in individual‐level information, while individual‐patient‐level data (IPD) are hard to obtain. Combined modeling may take advantage of both sources.
Liang Yang +6 more
wiley +1 more source
Neuroinflammation demonstrated by 11C‐ER176 PET with amyloid and tau pathology
Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.Abstract INTRODUCTION Understanding neuroinflammation across the Alzheimer's disease (AD) spectrum is essential to elucidate disease mechanisms and individualize therapy. METHODS Human microglial translocator protein (TSPO) expression under inflammatory stimuli was assessed by immunoblot experiments.
Mahathi Kandimalla +17 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 109-119, January 2026.Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang +17 more
wiley +1 more source
Eosinophilic Esophagitis in the Middle East: Insight From a Comprehensive Systematic Review
JGH Open, Volume 10, Issue 1, January 2026.ABSTRACT Background Eosinophilic esophagitis (EoE) is a chronic, immune‐mediated inflammatory disease of the esophagus, defined by esophageal dysfunction and dense eosinophilic infiltration (≥ 15 eosinophils per HPF) in biopsies, after exclusion of other causes.
Nouran Alwisi +2 more
wiley +1 more source
Drugs in focus: Budesonide and its role in paediatric gastrointestinal disorders
Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 1, Page 60-69, January 2026.Abstract Budesonide is a glucocorticoid with strong topical anti‐inflammatory properties and minimal systemic effects due to extensive first‐pass hepatic metabolism. It is designed for targeted delivery within the gastrointestinal (GI) tract and is available in oral and rectal formulations.
Sohail Aziz +11 more
wiley +1 more source