Enhancing G‐Quadruplex Binding: Rational Design and Biophysical Evaluation of Dimeric Ligands
Fluorescence thermal shift assays, electrospray ionization‐mass spectrometry, CD spectroscopy, molecular modeling and cytotoxicity assays were enrolled to study the binding of a rationally designed anthraquinone‐based G‐quadruplex binder interacting with the nucleic acid as a molecular tweezer.
Matteo Giannangeli +8 more
wiley +1 more source
Don't Bypass When There's Bilevel Positive Airway Pressure (BiPAP): Successful Management of Respiratory Distress and Atrial Flutter in a 77-Year-Old Woman Using BiPAP. [PDF]
Davila-Cardona AU +4 more
europepmc +1 more source
Pigment‐Macromolecule Complexes Isolation from Sea Urchin Biomineral Waste for Coloring Materials
A methodology has been developed to extract the colored organic fraction occluded within seashell biomineral waste. Applied to sea urchin skeletons, free polyhydroxylated naphthoquinone (PHNQ) pigments and PHNQ‐macromolecule complexes are isolated. These complexes show superior pH stability in purple hues compared to free PHNQ, which shifts from red to
Claudio Ferreira +12 more
wiley +1 more source
Clinical Role of the Noninvasive Abdominal Fetal ECG in the Detection and Monitoring of Fetal Tachycardia. [PDF]
Chivers S +18 more
europepmc +1 more source
Evaluation of high-angle attack aerodynamic-derivative data and stall-flutter prediction techniques
Robert L. Halfman +2 more
openalex +1 more source
This study explores the chemical and physical mechanisms behind the distinct cracking patterns observed in the black‐painted areas of five works by Antonio Saura. Multiband imaging and portable digital microscopy were employed to document the morphology and distribution of crack patterns.
Margherita Gnemmi +7 more
wiley +1 more source
Retrospective, Multicenter Study of Lacosamide to Treat Neonatal Seizures
ABSTRACT Objective Most antiseizure medications (ASMs) are prescribed off label for neonates. Lacosamide's efficacy in infants and availability in intravenous formulation suggest potential utility for neonates. We evaluated the safety and efficacy of lacosamide for neonatal seizures. Methods This 10‐center, retrospective study of neonates with seizures
Alexandra Santana Almansa +15 more
wiley +1 more source
Anterior mitral isthmus line using pulsed-field ablation with the pentaspline catheter or radiofrequency ablation: procedural characteristics, safety, and mid-term outcomes. [PDF]
Brügger J +13 more
europepmc +1 more source
In a digital risk‐taking test, participants inflated a balloon to increase earned points at the risk of popping under different display and ambient lighting conditions. ABSTRACT Lighting from architectural fixtures and screens can have impacts beyond visual perception, such as occupants' cognitive functions and emotional states. Despite the ubiquity of
Naser Shehab, Dorukalp Durmus
wiley +1 more source

