Results 231 to 240 of about 2,311,044 (291)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Optimization of Forward Osmosis for Oil Refinery Effluent Desalination Using Response Surface Methodology. [PDF]

Membranes (Basel)
Ezugbe EO, Rathilal S, Tetteh EK.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Above-canopy versus below-canopy nitrogen addition affects nitrate leaching and mineralization but not greenhouse gas fluxes in a sessile oak stand. [PDF]

Sci Rep
Da Ros L, Anna B, Pietro P, Mirco R, Roberto T, Claudio M, Flavio F, Giustino T, Maurizio V.   +8 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Tunable and nonlinearity-enhanced dispersive-plus-dissipative coupling in photon-pressure circuits. [PDF]

Nat Commun
Kazouini M, Peter J, Guo ZE, Wilde B, Uhl K, Koelle D, Kleiner R, Bothner D.   +7 more
europepmc   +1 more source

Model evidence for distinct origins of glacial-interglacial and millennial signals in Greenland dust. [PDF]

Proc Natl Acad Sci U S A
Hopcroft PO, Rousseau DD.
europepmc   +1 more source

Treats or affection? Understanding reward preferences in Indian free-ranging dogs. [PDF]

Anim Cogn
Nandi S, Lahiri A, Pal TS, Roy A, Bairagya R, Bhadra A.   +5 more
europepmc   +1 more source

Multimodal assessment of arterial stiffness using photoplethysmography and laser Doppler flowmetry. [PDF]

NPJ Cardiovasc Health
Karimpour P, Ferizoli R, May JM, Kyriacou PA.   +3 more
europepmc   +1 more source