Results 181 to 190 of about 715,950 (248)

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Dose by design: How limits on nicotine flux and puff duration affect the abuse liability of electronic nicotine delivery systems. [PDF]

Drug Alcohol Depend
Bono RS, White AM, Imran R, Maldonado GT, Lipato T, Barnes AJ, Cobb CO.   +6 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

[Contribution to the establishment of reference ranges for total immunoglobulin E: a cross-sectional study among blood donors in Abidjan (Ivory Coast)]. [PDF]

Pan Afr Med J
Assi AUA, Adou AH, Goran-Kouacou APV, Memel LRC, Yéboah OR, Oura BDY, Seri YJ, Attoukoula ATE, Siransy KL, N'guessan K, Dassé SR.   +10 more
europepmc   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A numerical and experimental study of light obscuration in laparoscopy. [PDF]

BMC Surg
Najafabadi HH, Woo MW, Suresh V, Spence CJT, Teh EL, Cater JE.   +5 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Flow physics and modeling in extreme ultraviolet sources. [PDF]

Natl Sci Rev
Chong KL, Wang BF, Wang F, Yan R, Ding H, Sun C, Zhou Q.   +6 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Revealing crossed-beam energy transfer as the origin of asymmetric backscattering in hohlraums. [PDF]

Nat Commun
Hao L, Gong T, Huo WY, Li Z, Liu Y, Qiu J, Li Q, Zhao H, Pan K, Li S, Hou L, Liu Y, Liu X, Li Y, Zheng W, Cao L, Cai H, Wang L, Zhao Y, Dong Y, Wang F, Yang D, Yang J, Zhao Z, Zou S, Zhu S, Ding Y.   +26 more
europepmc   +1 more source