Results 61 to 70 of about 2,066,164 (253)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Three-phase PMSM Comparison between DTC and MPTC

Edison Journal for Electrical and Electronics Engineering
This paper compares the control performance, average switching frequency, and parameter robustness of a Direct Torque Control (DTC) system and a Predictive Torque Control (MPTC) system based on the stator magnetic flux coordinate system of a permanent ...
Saif Talal Bahar, Falah Hamode
doaj   +1 more source

Design and analysis of a 3D-flux flux-switching permanent magnet machine with SMC cores and ferrite magnets

AIP Advances, 2017
Since permanent magnets (PM) are stacked between the adjacent stator teeth and there are no windings or PMs on the rotor, flux-switching permanent magnet machine (FSPMM) owns the merits of good flux concentrating and robust rotor structure. Compared with
Chengcheng Liu, Youhua Wang, Gang Lei, Youguang Guo, Jianguo Zhu   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Research on sensorless control of induction motor with low switching frequency

工程科学学报
AC induction motors have been widely used in various industries, and their sensorless control system has the advantages of simple structure and low cost. To realize sensorless control of the induction motor, the rotor flux and speed must be observed. The
Xin QI, Jiashi REN, Xiangyang SHI, Yuhang ZHAO, Lingyi LI   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

The new flux switching motor : a DC motor without brushes [PDF]

This thesis is principally concerned with the theoretical modelling, design, manufacture, performance testing, and development of a new type of low-cost electronically-commutated doubly-salient wound-field brushless DC-motor, named the flux-switching ...
Wallace, Mark
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Optimization Design of a Novel Flux-Switching Transverse-Flux Permanent Magnet Tube Linear Motor

, 2021
International audienceA novel flux-switching transverse-flux permanent magnet tube linear motor (FSTFPMTLM) with oblique air-gap is proposed in this article, which combined the merits of the tube linear motor, the transverse-flux linear motor, and the ...
Gillon, Frederic, Gong, Jinlin, Fu, Dongshan, Xu, Yanliang, Wu, Xiaojie, Bracikowski, Nicolas, Jia, Zeyu   +6 more
core   +1 more source

Fixed Switching Frequency Direct Model Predictive Control of Synchronous Reluctance Machines Based on Stator Flux Gradients

IEEE Access
This paper proposes a direct model predictive control method with a fixed switching frequency for stator flux control of a synchronous reluctance machine.
Ivana Zagorscak, Luka Pravica, Igor Erceg, Sandor Iles   +3 more
doaj   +1 more source