Results 61 to 70 of about 6,036 (297)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A New Concept for Deeper Integration of Converters and Drives in Electrical Machines: Simulation and Experimental Investigations

Open Physics, 2019
This paper introduces a new concept for integrated electrical motor drives (IEMD) with the aim of minimizing the number of inverter’s power switching components. The latter is switched reluctance motor (SRM) based.
Ghossini Hossam Al, Dang Thu Thuy, Duchesne Stéphane   +2 more
doaj   +1 more source

Discontinuous Pulse Width Modulation In Flux Angle Control Of Induction Motors [PDF]

International Journal of Research and Technology in Electrical Industry
In this study, flux angle control (FAC) with discontinuous modulation is presented for induction motor drives with the aim of optimizing motor and inverter losses under light load conditions.
Mohammad Reza Mohebbi, Davood Arab Khaburi   +1 more
doaj   +1 more source

Flux synthesizing linear induction motor with super multiphase switching

Electrical Engineering in Japan, 1992
AbstractA novel concept of structure and control of linear induction motors (LIMs) called “Flux Synthesizing Linear Induction Motors (FSLIMs),” is proposed where each slot has a conductor carrying an electric current whose amplitude and phase angle are controlled with super multiphase switching devices.
Koseki, Takafumi, Morizane, Toshimitsu, Masada, Eisuke   +2 more
openaire   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Design and analysis of a 3D-flux flux-switching permanent magnet machine with SMC cores and ferrite magnets

AIP Advances, 2017
Since permanent magnets (PM) are stacked between the adjacent stator teeth and there are no windings or PMs on the rotor, flux-switching permanent magnet machine (FSPMM) owns the merits of good flux concentrating and robust rotor structure. Compared with
Chengcheng Liu, Youhua Wang, Gang Lei, Youguang Guo, Jianguo Zhu   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Optimization od the Operation Behaviour of a Pemanent Magnet Excited Transverse Flux Motor for Direct Servo-Drive Applications Uve Werner

Scientific Journal of Gdynia Maritime University, 2017
This paper presents a control based upon optimised current waveforms with switching on current harmonics to achieve an accurate position and speed control with reduced ripples in torque shape for a transverse flux motor.
U. Wemer
doaj  

Research on sensorless control of induction motor with low switching frequency

工程科学学报
AC induction motors have been widely used in various industries, and their sensorless control system has the advantages of simple structure and low cost. To realize sensorless control of the induction motor, the rotor flux and speed must be observed. The
Xin QI, Jiashi REN, Xiangyang SHI, Yuhang ZHAO, Lingyi LI   +4 more
doaj   +1 more source