Results 241 to 250 of about 1,363,455 (339)

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source

Pedal effect: aerobic and facultative anaerobic Enterobacter hormaechei maintain the homeostasis of the house fly gut microbiota under different oxygen conditions. [PDF]

Parasit Vectors
Zhang K, Wang S, Li Y, Zhang X, Yin Y, Kong X, Liu W, Yao D, Zhang R, Zhang Z.   +9 more
europepmc   +1 more source

Feasibility investigation on ductile machining of single-crystal silicon for deep micro-structures by ultra-precision fly cutting

, 2019
Zhanwen Sun, Suet To, KM Yu
openalex   +2 more sources

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

Advanced Science, EarlyView.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li, Huiyang Huang, Cunhao Hu, Xuan Zhang, Song Lin, Xiaodan Huang, Ti‐fei Yuan, Kwok‐Fai So, Lu Huang, Chaoran Ren, Qian Tao   +10 more
wiley   +1 more source

Initial insights into using outline-based geometric morphometrics of the larval cephaloskeleton to identify forensically important calliphorids in Thailand. [PDF]

J Med Entomol
Kanta W, Sanit S, Sukontason KL, Dujardin JP, Dujardin S, Limsopatham K.   +5 more
europepmc   +1 more source

Directions for bringing over seeds and plants, from the East-Indies and other distant countries, in a state of vegetation: : together with a catalogue of such foreign plants as are worthy of being encouraged in our American colonies, for the purposes of medicine, agriculture, and commerce. To which is added, the figure and botanical description of a new sensitive plant, called Dionaea muscipula: or, Venus's fly-trap /

John Ellis
openalex   +2 more sources

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

Advanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang, Honglin Tan, Colleen Russell, Mikolaj Walczak, Dawei Gao, Guanda Qiao, Xiaoxuan Fan, Chengyan Chu, Miroslaw Janowski, Piotr Walczak, Yajie Liang   +10 more
wiley   +1 more source

Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing

Advanced Science, EarlyView.
CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian‐Kang Zhu   +15 more
wiley   +1 more source

Unlocking bioenergy potential in heavy metal polluted soils: synergistic advanced solid-state fermentation and combustion for valorization of sweet sorghum. [PDF]

BMC Plant Biol
Xue ZC, Liu J, Zhang CM, Lv P, Jiao ZY, Li SZ.   +5 more
europepmc   +1 more source

SYNTHESIS OF OXAZOLONE AND IMIDAZOLONE DERIVATIVES IN PRESENCE OF H2O2 PROMOTED FLY ASH AS A NOVEL AND EFFICIENT CATALYST

, 2017
Samieh Fozooni, Hamid Khoshdast, Hassan Hassani, Hooshang Hamidian   +3 more
openalex   +1 more source