Results 51 to 60 of about 39,518 (215)

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Cloud-Assisted UAV Data Collection for Multiple Emerging Events in Distributed WSNs

Sensors, 2017
In recent years, UAVs (Unmanned Aerial Vehicles) have been widely applied for data collection and image capture. Specifically, UAVs have been integrated with wireless sensor networks (WSNs) to create data collection platforms with high flexibility ...
Huiru Cao, Yongxin Liu, Xuejun Yue, Wenjian Zhu   +3 more
doaj   +1 more source

Orbital Maintenance of a Constellation of CubeSats for Internal Gravity Wave Tomography

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2020
The advent of radio occultation (RO) instruments aboard CubeSats leads to the possibility of a mission to sound atmospheric internal gravity waves if such satellites are deployed in close-flying constellation.
Stephen Leroy, Riley Fitzgerald, Kerri Cahoy, James Abel, James Clark   +4 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt, Eya Khadhraoui, Sebastian J. Müller, Katja Neumann, Hendrik Mattern, Sven G. Meuth, Valentina Perosa, Andreas Charidimou, Stefanie Schreiber   +8 more
wiley   +1 more source

Research on the Influence of Cracked Control Surface on the Gust Response of High-Aspect-Ratio Flying Wing

Aerospace
Flying-wing aircraft based on high-aspect-ratio wings are a popular configuration for many aerospace engineering applications. Cracked (or cross) control surface structures can adjust the aerodynamic characteristics of flying-wing aircraft.
Mingdong Wang, Xiangmian He, Yuguang Bai, Sheng Zhang   +3 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen, Yuying Zhang, Heyu Zhang, Jinming Zhang, Ningning Wang, Xintong Guo, Yicong Liu, Yue Liu, Xiangsong Zhang, Ziyi Chen, Guanzhong Ni   +10 more
wiley   +1 more source

Aerodynamic Lift Modeling and Analysis of a Bat-like Flexible Flapping-Wing Robot

Modelling
In the research and development system of bat-like flapping-wing flying robots, lift modeling and numerical analysis are the key theoretical basis, which will directly affect the construction of the body structure and flight control system.
Bosong Duan, Zhaoyang Chen, Shuai Wang, Junlei Liu, Bingfeng Ju, Anyu Sun   +5 more
doaj   +1 more source

Consequences of EEG electrode position error on ultimate beamformer source reconstruction performance

Frontiers in Neuroscience, 2014
Inaccuracy of EEG electrode coordinates forms an error term in forward model generation and ultimate source reconstruction performance. This error arises from the combination of both intrinsic measurement noise of the digitization apparatus and manual ...
Sarang S Dalal, Stefan eRampp, Florian eWillomitzer, Svenja eEttl   +3 more
doaj   +1 more source