Results 61 to 70 of about 1,742,961 (319)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Cognitive Assessment in Patients with Traumatic Brain Injury

Brazilian Neurosurgery, 2017
Traumatic brain injury (TBI) is a major public health problem in Western countries. A TBI brings many negative consequences, including behavioral and cognitive changes, which affect social adjustment and the performance of functional activities ...
Ana Luiza Zaninotto, Vinícius Monteiro de Paula Guirado, Mara Cristina Souza De Lucia, Almir Ferreira de Andrade, Manoel Jacobsen Teixeira, Wellingson Silva Paiva   +5 more
doaj   +1 more source

Whole‐Body Pattern of Muscle Degeneration and Progression in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize whole‐body intramuscular fat distribution pattern in patients with sarcoglycanopathies and explore correlations with disease severity, duration and age at onset. Methods Retrospective, cross‐sectional, multicentric study enrolling patients with variants in one of the four sarcoglycan genes who underwent whole‐body ...
Laura Costa‐Comellas, Mauro Monforte, Angel Sanchez‐Montañez, Penélope Romero‐Duque, Elena Pegoraro, Jordi Díaz‐Manera, Dmitry Vlodavets, Lorenzo Maggi, Marco Moscatelli, Adele D‘Amico, Montse Olivé, Jorge Alonso‐Pérez, Giacomo Comi, José Miguel Escudero‐Fernández, Gabriela S. Urcuyo, Anna Pichiecchio, Angela Berardinelli, Kristl G. Claeys, Claudio Bruno, Chiara Panicucci, Sara Bortolani, Eleonora Torchia, Enzo Ricci, Soledad Monges, Jorge A. Bevilacqua, Jorge Diaz‐Jara, Maggie C. Walter, Simone Thiele, Nicoline Løkken, John Vissing, Susana Quijano‐Roy, Robert Y. Carlier, Nicol C. Voermans, Chiara Marini‐Bettolo, Michela Guglieri, Volker Straub, Lea Leonardis, Francina Munell, David Gómez‐Andrés, Giorgio Tasca   +39 more
wiley   +1 more source

Parallel numerical simulation of oscillating airfoil NACA0015 in the channel due to flutter instability

EPJ Web of Conferences, 2014
The work is devoted to 3D and 2D parallel numerical computation of pressure and velocity fields around an elastically supported airfoil self-oscillating due to interaction with the airflow.
Řidký Václav, Šidlof Petr
doaj   +1 more source

Magnetic Proximity Effect in Perovskite Superconductor/Ferromagnet Multilayers

, 2004
$\mathrm{YBa_2Cu_3O_7/La_{2/3}Ca_{1/3}MnO_3}$ superconducting/ferromagnetic (SC/FM) multilayers have been studied by neutron reflectometry. Evidence for a characteristic difference between the structural and magnetic depth profiles is obtained from the ...
A. I. Buzdin, B. Keimer, C. Bernhard, Ch. Niedermayer, F. Treubel, G. Cristiani, H-U. Habermeier, H. U. Habermaier, J. Chakhalian, J. Hoppler, J. Stahn, J. Voigt, P. Mikulík, P. W. Anderson, T. Gutberlet, V. Holý   +15 more
core   +1 more source

Diagnostic Utility of the ATG9A Ratio in AP‐4–Associated Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adaptor protein complex 4–associated hereditary spastic paraplegia (AP‐4‐HSP), a childhood‐onset neurogenetic disorder and frequent mimic of cerebral palsy, is caused by biallelic variants in the adaptor protein complex 4 (AP‐4) subunit genes (AP4B1 [for SPG47], AP4M1 [for SPG50], AP4E1 [for SPG51], and AP4S1 [for SPG52]).
Habibah A. P. Agianda, Hyo‐Min Kim, Nicole Battaglia, Joshua Rong, Amy Tam, Enrique Gonzalez Saez‐Diez, Cornelius F. Boerkoel, Afshin Saffari, Vicente Quiroz, Luca Schierbaum, Zainab Zaman, Katerina Bernardi, Darius Ebrahimi‐Fakhari   +12 more
wiley   +1 more source

Scalability of the parallel CFD simulations of flow past a fluttering airfoil in OpenFOAM

EPJ Web of Conferences, 2015
The paper is devoted to investigation of unsteady subsonic airflow past an elastically supported airfoil during onset of the flutter instability. Based on the geometry, boundary conditions and airfoil motion data identified from wind-tunnel measurements,
Šidlof Petr, Řidký Václav
doaj   +1 more source

Effect of Spin-Flip Scattering on Electrical Transport in Magnetic Tunnel Junctions

, 2002
By means of the nonequilibrium Green function technique, the effect of spin-flip scatterings on the spin-dependent electrical transport in ferromagnet-insulator-ferromagnet (FM-I-FM) tunnel junctions is investigated.
Biao Jin, De Teresa, Fert, Gang Su, Gijs, Haug, Jaffrès, Jullière, Meservey, Moodera, Moodera, Moodera, Prinz, Qing-Rong Zheng, Slonczewsky, Vedyayev, Wolf, Zhen-Gang Zhu   +17 more
core   +2 more sources

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Exchange bias in phase-segregated Nd2/3Ca1/3MnO3 as a function of temperature and cooling magnetic fields

, 2014
Exchange bias (EB) phenomena have been observed in Nd2/3Ca1/3MnO3 colossal magnetoresistance perovskite below the Curie temperature $T_{C}$ = 70 K and attributed to an antiferromagnetic (AFM) - ferromagnetic (FM) spontaneous phase segregated state of ...
Desnenko, Vladimir, Dolya, Sergiy, Feher, Alexander, Fertman, Elena, Kajnakova, Marcela, Pozhar, Liudmia A.   +5 more
core   +1 more source