Results 241 to 250 of about 172,524 (297)

Neurobehavioral therapy in functional seizures: Investigation of mechanism of action with resting‐state functional magnetic resonance imaging

open access: yesEpilepsia, EarlyView.
Abstract Objective Functional seizures (FS) often disrupt the key regions integral to cognitive processing and emotional regulation (anterior insula, anterior cingulate, and temporoparietal junction). We investigated the potential neurophysiologic mechanism of action (MOA) of neurobehavioral therapy (NBT) using resting‐state functional MRI seed‐based ...
Jerzy P. Szaflarski   +8 more
wiley   +1 more source

Predictors of atypical language lateralization in focal epilepsy: A mega‐analysis of fMRI evidence

open access: yesEpilepsia, EarlyView.
Abstract Objective To identify predictors of language lateralization derived from functional magnetic resonance imaging (fMRI) in children and adults with left‐ and right‐sided focal epilepsy. Methods We conducted a mega‐analysis of data from 914 individuals from 24 samples. We used multilevel models to identify predictors of language lateralization in
Freya Prentice   +8 more
wiley   +1 more source

Distinct gray matter and metabolic characteristics in hypothalamic hamartoma network with different semiology

open access: yesEpilepsia, EarlyView.
Abstract Objective Hypothalamic hamartomas (HHs) are developmental malformations associated with focal epilepsy. We investigated the patterns of gray matter morphology and cerebral metabolism in individuals with HHs, with and without focal to bilateral tonic–clonic seizures (FBTCSs), aiming to clarify the accompanying network abnormalities.
Yihe Wang   +12 more
wiley   +1 more source

The clinical relevance of healthy neurodevelopmental connectivity in childhood and adolescence: a meta-analysis of resting-state fMRI. [PDF]

open access: yesFront Neurosci
Tapia Medina MG   +5 more
europepmc   +1 more source

Comparison of children and adults undergoing subdural grid electrode implantation or stereoelectroencephalography in a refractory epilepsy cohort from four European centers

open access: yesEpilepsia, EarlyView.
Abstract Objective Children with refractory focal epilepsy differ from adults, although many centers will offer invasive electroencephalography (iEEG) to both. Outcomes in terms of likelihood of resection and subsequent seizure outcome after either subdural grid electrode implantation (SDE) or stereoelectroencephalography (SEEG) have, however, not been
Matea Rados   +21 more
wiley   +1 more source

Enhancing cerebral infarct classification by automatically extracting relevant fMRI features. [PDF]

open access: yesBrain Inform
Dobromyslin VI   +2 more
europepmc   +1 more source

Seizure‐onset zone lateralization in temporal lobe epilepsy using 7T rs‐fMRI: Direct comparison with 3T rs‐fMRI

open access: yesEpilepsia, EarlyView.
Abstract Objective Resting‐state functional magnetic resonance imaging (rs‐fMRI) at ultra‐high field strengths (≥7T) is known to provide superior signal‐to‐noise to comparable acquisitions at lower field strengths. In this study, we provide a direct comparison of the seizure onset‐zone (SOZ) lateralizing ability of 7T rs‐fMRI and 3T rs‐fMRI. Methods We
Alfredo Lucas   +8 more
wiley   +1 more source

Compensatory cerebellar activation during fluid intelligence processing following mild traumatic brain injury. [PDF]

open access: yesSci Rep
Leibovici A   +19 more
europepmc   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications. 1. Use of the EEG in drug development and characteristics of the model

open access: yesEpilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof‐of‐principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalography (EEG) response (PPR) as a surrogate for seizures, is currently the only human model that allows POP trials of investigational compounds after ...
Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

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