Results 101 to 110 of about 4,068,625 (378)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Focal Infection of Dental Origin - (Review article)

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2005
Theory of focal infection has been the topic discussed and refused many times. Recently, with fast improvement of diagnostic and therapeutic procedures it has become a very popular theme among specialists again.
P. Závodský, P. Bednář
doaj  

The Evaluation of the Occurrence of the Oral Focal Infection. The Group of 278 Patients

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2016
Introduction and aims: Focal infection is defined as a type of disease when the chronic disease arises in the remote organ or tissue from the primary locus of the infection.
M. Chalupová, H. Hecová
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Optimal population-level infection detection strategies for malaria control and elimination in a spatial model of malaria transmission

open access: yes, 2015
Mass campaigns with antimalarial drugs are potentially a powerful tool for local elimination of malaria, yet current diagnostic technologies are insufficiently sensitive to identify all individuals who harbor infections.
Bever, Caitlin A.   +5 more
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Xanthogranulomatous pyelonephritis: presentation and management [PDF]

open access: yes, 2019
Xanthogranulomatous pyelonephritis (XGP) is characterized by the presence of lipid-laden foamy macrophages with both acute and chronic phase inflammatory cells.
Badiu, Dumitru Cristinel   +8 more
core   +1 more source

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