Results 81 to 90 of about 368,302 (254)

A Note On The Stability Of The Focal Loss.

Trans. Mach. Learn. Res.
The Focal Loss is a widely deployed loss function that is used to train various types of deep learning models. It is a modification of the cross-entropy loss designed to mitigate the effect of class imbalance in dense object detection tasks. By downweighting the losses for easy, correctly classified samples, the method places more emphasis on harder ...
van Leeuwen, Martijn, Haak, Koen, Saygili, Görkem, Postma, Eric, Ong, Sharon   +4 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Loss of inhibition in sensorimotor networks in focal hand dystonia

NeuroImage: Clinical, 2018
OBJECTIVE: To investigate GABA-ergic receptor density and associated brain functional and grey matter changes in focal hand dystonia (FHD). METHODS: 18 patients with FHD of the right hand and 18 age and gender matched healthy volunteers (HV) participated in this study.
Gallea, Cecile, Herath, Priyantha, Voon, Valerie, Lerner, Alicja, Ostuni, John, Saad, Ziad, Thada, Shantalaxmi, Jeffrey, Solomon, Horovitz, Silvina G., Hallett, Mark   +9 more
openaire   +4 more sources

RCLNet: an effective anomaly-based intrusion detection for securing the IoMT system

Frontiers in Digital Health
The Internet of Medical Things (IoMT) has revolutionized healthcare with remote patient monitoring and real-time diagnosis, but securing patient data remains a critical challenge due to sophisticated cyber threats and the sensitivity of medical ...
Jamshed Ali Shaikh, Chengliang Wang, Wajeeh Us Sima Muhammad, Muhammad Arshad, Muhammad Owais, Rana Othman Alnashwan, Samia Allaoua Chelloug, Mohammed Saleh Ali Muthanna, Mohammed Saleh Ali Muthanna   +8 more
doaj   +1 more source

GFADE: generalized feature adaptation and discrimination enhancement for deepfake detection [PDF]

PeerJ Computer Science
With the rapid advancement of deep generative techniques, such as generative adversarial networks (GANs), the creation of realistic fake images and videos has become increasingly accessible, raising significant security and privacy concerns.
ZhiYong Tian, Junkai Yi
doaj   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Optimized Hybrid Focal Margin Loss for Crack Segmentation

2022 International Conference on Digital Image Computing: Techniques and Applications (DICTA), 2022
Many loss functions have been derived from cross-entropy loss functions such as large-margin softmax loss and focal loss. The large-margin softmax loss makes the classification more rigorous and prevents overfitting. The focal loss alleviates class imbalance in object detection by down-weighting the loss of well-classified examples. Recent research has
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source