Results 71 to 80 of about 120,639 (257)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Source characteristics and seismogenic structure of small-to-moderate earthquakes in Xinfengjiang Reservoir area, Guangdong Province

open access: yes地球与行星物理论评
On March 19, 1962, the Xinfengjiang Reservoir in Heyuan City, Guangdong Province, induced an M6.1 earthquake as it approached its first full-capacity impoundment peak.
Shufeng Xu   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

川南长宁地区关键震源参数与地震活动性演化规律及成因研究

open access: yesDizhen xuebao
基于2010年10月至2022年7月期间长宁地区MS≥3.0地震事件,采用CAP全波形反演获取震源机制解,并结合阻尼最小二乘法反演该区域应力场的时空变化特征;同时利用多台联合反演方法提取震源参数,结合b值演化分析地震活动性演变过程。结果表明:长宁地区地震以逆冲型和走滑型为主,震源深度浅,地震活动集中分布于华蓥山断裂带西侧,最大主应力方向为WNW-ESE,整体应力场稳定,但在2019年MS6.0强震后出现短期扰动;震源参数(应力降、拐角频率、震源半径)与震级呈显著相关性,应力降均值为7.94 MPa ...
Haoyue Gong, Jun Hu
doaj   +1 more source

Stress inversion of earthquake focal mechanism solutions from onshore and offshore Norway

open access: yesNorsk Geologisk Tidsskrift, 2000
A comprehensive compilation of 112 earthquake focal mechanism solutions in Norway and adjacent areas has been completed, including 7 previously unpublished solutions for recent earthquakes determined as part of the NEONOR (Neotectonics in Norway) project.
Erik C. Hicks   +2 more
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

新疆柯坪地区地震震源机制解与现今应力场特征

open access: yesDizhen xuebao
基于全球质心矩张量GCMT资料,搜集整理了1991—2005年新疆柯坪地区中强地震的震源机制解;利用新疆地震台网2004—2024年宽频带波形数据,采用CAP方法补充计算了区域内MS≥3.5地震的震源机制解;采用区域应力张量阻尼方法(MSATSI)反演了柯坪地区应力空间分布,探讨了其应力场分区特征。结果表明,柯坪地区地震事件的震源机制解以逆断型为主,震源深度集中在5—30 km范围内,其中西部地区地震震源深度由南向北逐渐增加;东部地区地震事件以2024年乌什MS7.1地震序列为主,震源深度主要集中在5 ...
Mingwen Deng   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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