Results 91 to 100 of about 742,886 (286)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Characteristics of focal mechanisms in Chile subduction

Geodesy and Geodynamics, 2012
We use the Centroid Moment Tensor (CMT) solution of the earthquakes occurred in Chile subduction to analyze the characteristics of focal mechanisms. We define the angle between P, B, and T axes of focal mechanisms and three stress axes of tectonic stress
Wang Xiaoshan, Diao Guiling, Feng Xiangdong, Yang Yaqiong   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Analysis of Focal Mechanisms Using Waveform Inversion; Case Study of Pidie Jaya Earthquake December 7, 2016

Journal of Aceh Physics Society, 2018
Salah satu gempa bumi yang berdampak pada kerusakan rumah penduduk telah terjadi di Sumatra tepatnya adalah daerah Pidie Jaya pada tanggal 7 Desember 2016, sebesar Mw 6.5.
Qadariyah Qadariah, Andrean VH Simanjuntak, Muksin Umar   +2 more
doaj  

Comparison of solutions for microseismic focal mechanism estimation [abstract]. [PDF]

Geology, Geophysics & Environment, 2016
Paweł Wandycz, Eryk Święch, Andrzej Pasternacki   +2 more
openaire   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Focal Mechanisms of Medium-Small Earthquakes in Taiyuan Basin Since 2016

Taiyuan Ligong Daxue xuebao
Purposes On the basis of previous researches and the latest broadband digital waveform data from the Shanxi Regional Seismic Network, multiple methods are employed to obtain updated focal mechanism solutions for earthquakes with ML≥2.5 that occurred in ...
LI Jiali, LI Bin, JIN Yidan, ZHAO Xiaoyun, LI Zihong   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Coulomb stress effects of the April 3, 2024 Hualien, Taiwan, China MS 7.3 earthquake on the surrounding faults and subsequent April 23, 2024 MS 6.2 and MS 6.3 earthquakes

Dizhi lixue xuebao
Objective  To determine the rupture mode of the MS 7.3 earthquake in Hualien, Taiwan, China on April 3, 2024 and its triggering effect on subsequent seismic events in the surrounding area, the co-seismic displacement field and the induced areal strain ...
GU Peiyuan, WAN Yongkui, SONG Zeyao, WANG Runyan, GUAN Zhaoxuan   +4 more
doaj   +1 more source