Results 141 to 150 of about 7,106,654 (320)
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Do large caves exist deep underground? Through seismological investigations, we speculate the existence of a large geological cave about 7 km beneath the surface.
Tingxiao Xue, Liang Wang
doaj +1 more source
<p>Welcome to the Focal Mechanism Earthquake Dataset repository! This dataset contains valuable information on earthquake events, including their location, magnitude, depth, and focal mechanism solutions.
G Babu, Vivek
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Automatic Determination of Focal Mechanism Solution Using Initial Motion Polarity of P Waves.
自動的に、P波の初動極性を取得し、発震機構解を決定し、十分な精度で発震機構解が決定できているか否かを判別する手法を提案した。P波の初動極性を取得する際には、まず、ベッセルバンドパスフィルタを適用し、次に、ARモデルを用いてP波の初動到達時を得、ARフィルタを適用した。発震機構解の決定には、グリッドサーチによる手法を用いた。十分な精度で発震機構解が決定できているか否かを判別するために、解の安定性、過去に発生した地震の発震機構解等から総合的に判断し、発震機構解の決定精度の評価を行った。気象庁によって読みとられた初動極性の70%が、本手法を適用することによって得られた。また、両者でくい違った験測を行っているのは全体の3.5%以下であり、十分な精度で初動極性の自動験測が行われた。さらに ...
openaire +2 more sources
A theory of unstructured bargaining using distribution-valued solution concepts [PDF]
In experiments it is typically found that many joint utility outcomes arise in any given unstructured bargaining game. This suggests using a positive unstructured bargaining concept that maps a bargaining game to a probability distribution over outcomes ...
David H. Wolpert, James Bono
core
Online mechanism design for electric vehicle charging [PDF]
The rapid increase in the popularity of electric vehicles (EVs) and plug-in hybrid electric vehicles (PHEVs) is expected to place a considerable strain on the existing electricity grids, due to the high charging rates these vehicles require.
Enrico H. Gerding +14 more
core +3 more sources
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Full agreement and the provision of threshold public goods [PDF]
We report threshold public good experiments in which group members not only need to be individually willing to contribute enough to provide the public good but also have to agree with each other on what every group members should contribute.
Edward J. Cartwright, Federica Alberti
core

