Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
An Online Mechanism for Multi-Speed Electric Vehicle Charging [PDF]
As plug-in electric vehicles become more widespread, their charging needs to be coordinated, in order to ensure that capacity constraints are not exceeded.
Enrico H. Gerding +14 more
core +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
WinFOC: A new software for focal mechanisms solution
This study comprises a new focal mechanism solution (OMC) program that can be used for scientific research and educational purposes. In addition, results of applied researches performed in the frame of this study, are also given using this software which is called WinFOC. In order to compute fault plane solutions and investigate kinematics of different
ÖZYALIN, ŞENOL, POLAT, ORHAN DEDE
openaire +1 more source
On Maskin monotonicity of solution based social choice rules [PDF]
Howard (1992) argues that the Nash bargaining solution is not Nash implementable, as it does not satisfy Maskin monotonicity. His arguments can be extended to other bargaining solutions as well.
Walter Trockel, Claus-Jochen Haake
core
Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
core +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Study on the Focal Mechanism of the M5.1 Badong Earthquake in Hubei
The focal mechanism solutions of the M5. 1 Badong earthquake and subsequent 34 aftershocks at ML 2. 0 or more were calculated using the P-wave first motion method; the main earthquake was normal fault dip slip type, and the slip types of the seismogenic ...
Chen Junhua, Zhao Lingyun, Wu Haibo
doaj +1 more source
On the Role of Non-equilibrium Focal Points as Coordination Devices [PDF]
Considering a pure coordination game with a large number of equivalent equilibria, we argue, first, that a focal point that is itself not a Nash equilibrium and is Pareto dominated by all Nash equilibria, may attract the players' choices.
Nicolaas J. Vriend +1 more
core +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

