Results 101 to 110 of about 6,474,936 (293)

Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]

open access: yes
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس   +1 more
core   +1 more source

A TEST OF THE OBLIQUE-RIFTING MODEL FOR TRANSFER ZONE DEFORMATION IN THE NORTHERN FEN-WEI RIFT: IMPLICATIONS FROM THE 1989 M 6.1 DATONG-YANGGAO EARTHQUAKE SWARM

open access: yesГеодинамика и тектонофизика, 2019
Tectonophysical experiments show that the evolution of the Fen-Wei Rift is controlled by oblique rifting. A key characteristic of the model in our study is that the western and eastern borders of the transfer zone between the adjacent NEE-striking ...
Yan-Qun Zhuo   +3 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

On the Role of Non-equilibrium Focal Points as Coordination Devices [PDF]

open access: yes
Considering a pure coordination game with a large number of equivalent equilibria, we argue, first, that a focal point that is itself not a Nash equilibrium and is Pareto dominated by all Nash equilibria, may attract the players' choices.
Nicolaas J. Vriend   +1 more
core   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Proximal femoral focal deficiency : a case report [PDF]

open access: yes, 2008
Proximal Femoral Focal Deficiency (PFFD) is a rare and complex congenital anomaly (1:50,000-200,000 population) that results in varying degrees of femoral hypoplasia with limb shortening and pelvic abnormalities.
Ellul, Marthese   +3 more
core  

Coulomb stress effects of the April 3, 2024 Hualien, Taiwan, China MS 7.3 earthquake on the surrounding faults and subsequent April 23, 2024 MS 6.2 and MS 6.3 earthquakes

open access: yesDizhi lixue xuebao
Objective  To determine the rupture mode of the MS 7.3 earthquake in Hualien, Taiwan, China on April 3, 2024 and its triggering effect on subsequent seismic events in the surrounding area, the co-seismic displacement field and the induced areal strain ...
GU Peiyuan   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

FocoNet: Transformer‐Based Focal‐Mechanism Determination

open access: yesJournal of Geophysical Research: Machine Learning and Computation
Traditional focal‐mechanism determination primarily relies on fitting the first‐motion polarities with grid‐search algorithms. We developed a machine‐learning model, FocoNet, to include more seismic information into focal mechanism determination.
Xiaohan Song   +3 more
doaj   +1 more source

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