Results 131 to 140 of about 6,474,936 (293)
Dizhi lixue xuebaoObjective The Wushi region in Xinjiang is located at the intersection of multiple tectonic units, characterized by frequent tectonic activity, making it a critical region for stress concentration and release.
SONG Zeyao +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Harnessing the Power of Focal Points To Measure Social Agreement [PDF]
This paper reports results from an application of Thomas Schelling’s (1960) concept of a focal point to the measure of social agreement on the received tone of media content.
Stuart Soroka, Jim Engle-Warnick
core
地球与行星物理论评Do large caves exist deep underground? Through seismological investigations, we speculate the existence of a large geological cave about 7 km beneath the surface.
Tingxiao Xue, Liang Wang
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
<p>Welcome to the Focal Mechanism Earthquake Dataset repository! This dataset contains valuable information on earthquake events, including their location, magnitude, depth, and focal mechanism solutions.
G Babu, Vivek
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Automatic Determination of Focal Mechanism Solution Using Initial Motion Polarity of P Waves.
Papers in Meteorology and Geophysics, 2002 自動的に、P波の初動極性を取得し、発震機構解を決定し、十分な精度で発震機構解が決定できているか否かを判別する手法を提案した。P波の初動極性を取得する際には、まず、ベッセルバンドパスフィルタを適用し、次に、ARモデルを用いてP波の初動到達時を得、ARフィルタを適用した。発震機構解の決定には、グリッドサーチによる手法を用いた。十分な精度で発震機構解が決定できているか否かを判別するために、解の安定性、過去に発生した地震の発震機構解等から総合的に判断し、発震機構解の決定精度の評価を行った。気象庁によって読みとられた初動極性の70%が、本手法を適用することによって得られた。また、両者でくい違った験測を行っているのは全体の3.5%以下であり、十分な精度で初動極性の自動験測が行われた。さらに ...
openaire +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source