Results 121 to 130 of about 120,186 (297)
, 2022 Accurate and precise location and focal mechanism of aftershocks is a fundamental topic in seismology. However, nearfield seismic observations are usually not available for high-resolution source studies, or even when they are available high frequency ...
Fadil, Wardah Shafiqah Binti Muhammad +12 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
El terremoto de magnitud Mw 8.8 de Kamchatka del 29 de julio de 2025 representa uno de los mayores eventos sísmicos registrados en la zona de subducción de Kuril-Kamchatka.
Carrera Cevallos, Amilcar
core +2 more sources
Focal Mechanism and Rupture Process of 2004 Alhoceima (Morocco, Mw=6.2) Earthquake from Teleseismic and Regional Broad-Band Data. [PDF]
, 2004 We have study the focal mechanism of the 2004 Alhoceima (Morocco, Mw=6.2) earthquake using teleseismic and regional broad-band data. The solution obtained shows strike slip motion with planes striking respectively on NNE-SSW and WNW-ESE direction and ...
Buforn, E +5 more
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Probabilistic waveform inversion for focal parameters of local earthquakes
, 2005 For a given earth model and hypocenter location, short-period local waveforms are inverted for the six unknown moment tensor rate functions (MTRFs) by a linear procedure.
Z. Wéber, Wéber, Z.
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source