Results 181 to 190 of about 80,952 (305)

Vigabatrin (Sabril) for the Treatment of Refractory Complex Focal Seizures in Adults: Pharmacologic and Clinical Considerations. [PDF]

Cureus, 2023
Gatson TN, Freemont OA, Coleman RL, Lockett SJ, Spillers NJ, Ahmadzadeh S, Viswanath O, Varrassi G, Shekoohi S, Kaye AD.   +9 more
europepmc   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Early response rates with adjunctive cenobamate in uncontrolled focal seizures: Prospective analysis of a randomized, double-blind, placebo-controlled study in a multinational Asian population. [PDF]

Epilepsia
Kawai K, Choe E, Ferrari L, Heo K, Hong SB, Huang H, Iida K, Jeon YH, Jung J, Kamin M, Kim JH, Kim MW, Lee SK, Pan S, Park J, Pradhan P, Rosenfeld WE, Xu H, Yamamoto T, Misra SN.   +19 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effectiveness and safety of early add-on therapy with brivaracetam in patients with poorly controlled focal seizures in routine clinical practice: BRIV-add study. [PDF]

Epilepsia Open
Serrano-Castro PJ, Caballero-Martínez F, Campos-Lucas FJ, Campos-Fernández D, de Aguilar-Amat MJ, García A, Gifreu A, Santamaría-Rodríguez I, Poza JJ, Toledo-Argany M, Grupo de Investigadores Colaboradores.   +10 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Infantile TK2 Deficiency Causing Mitochondrial Encephalomyopathy With Migrating Focal Seizures. [PDF]

Neurology
Bergonzini L, Carli S, Pelle S, Pettenuzzo I, Bonetti S, Santi E, Visconti C, Maffei M, Sheremet M, Lamantea E, Marsala A, Klub O, Gentile V, Cordelli DM, Garone C.   +14 more
europepmc   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Electrocardiographic Markers of Sudden Unexpected Death Risk in Pediatric Epilepsy: A Comparative Study of Generalized and Focal Seizures. [PDF]

Diagnostics (Basel)
Karaca S, Özbingöl D, Karaca Özer P, Yavuz ML, Nişli K, Öztarhan K, Duman Kayar Ç, Öney C, Yıldız EP.   +8 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source