Plague history, Mongol history, and the processes of focalisation leading up to the Black Death: a response to Brack <i>et al.</i> [PDF]
Green MH, Fancy N.
europepmc +1 more source
[When hotlines remain cold: Psychological support in the time of pandemic]. [PDF]
Michaud L +4 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
[Classification of the intensity of interprofessional learning in the context of clinical placements: a proposal based on theoretical foundations in interprofessional education and the results of a narrative review]. [PDF]
Richard A +4 more
europepmc +1 more source
[Vulnerabilities, ethical responsibility and acceptance of otherness during the first Covid lockdown: A case study of a French Care Centre for Support and Prevention in Addictology]. [PDF]
Marcucci L, Nutini S.
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Putting the horse back in front of the cart: a critical reflection on the CIHR-IPPH dialogue on the future of Canada's public health systems. [PDF]
Hancock T, McLaren L.
europepmc +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source

