Results 101 to 110 of about 6,297,015 (317)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Notions of focus anaphoricity

, 2008
This article reviews some of the theoretical notions and empirical phenomena which figure in current formal-semantic theories of focus.
Rooth, Mats
core   +1 more source

The Relationship Between Physical Fitness And Academic Achievement: How Exercise Improves Concentration

Jurnal Stamina
Physical fitness plays a crucial role in enhancing students' focus and improving their learning outcomes. his study explores the relationship between physical fitness and academic achievement, with a particular focus on how regular exercise improves ...
Rahmat Iqbal, Dikdik Fauzi Dermawan, Rekha Ratri Julianti, Oktaviarini Yahya Rahmadhanty, Fahd Mukhtarsyaf   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Contrastive focus

, 2008
The article puts forward a discourse-pragmatic approach to the notoriously evasive phenomena of contrastivity and emphasis. It is argued that occurrences of focus that are treated in terms of "contrastive focus", "kontrast" (Vallduví & Vilkuna 1998) or ...
Zimmermann, Malte
core  

Dealing with two ‘SARS’ outbreaks in Nigeria: The public health implications

Public Health in Practice, 2021
Melody Okereke, Isaac Olushola Ogunkola, Yusuff Adebayo Adebisi, Don Eliseo Lucero-Prisno III   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Acquisition of non-contrastive focus in Russian by adult English-dominant bilinguals

Frontiers in Psychology
This study investigates the acquisition of sentence focus in Russian by adult English-Russian bilinguals, while paying special attention to the relative contribution of constituent order and prosodic expression.
Tatiana Luchkina, Tania Ionin, Maria Goldshtein   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source