Results 151 to 160 of about 3,290,780 (252)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Study Protocol: It is time to dig deeper: A cross-country implementation mapping study of the iFightDepression® (online self-management) tool. [PDF]

PLoS One
Rotter T, Petrovic M, Zarzycki M, Allenhof C, Schnitzspahn K, Toczyski P, Justicia A, Leal SA, Chan J, Leimhofer J, Scholze K, Hackel S, Sola VP, Hegerl U.   +13 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Amplifying community perspectives in Medicaid policymaking: findings from North Carolina. [PDF]

Health Aff Sch
Debab S, Repka S, Huber K, Austin A, Cholera R, Bleser W, Pokam Tchuisseu Y, Khayamian A, Seaman A, Thoumi A, Saunders R, Whitaker R.   +11 more
europepmc   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Front Matter

Global Focus
Global Focus
doaj  

Social Needs Screening Tools for Clinical Populations in Australia and New Zealand: A Scoping Review and Critical Analysis. [PDF]

Health Expect
Weld-Blundell I, Learmonth YC, Klaic M, Haartsen J, Ayton D, Kavanagh A, Hawkins MR, Marck CH.   +7 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Editorial Foreword

Global Focus
Global Focus
doaj  

Co-Design of an Electronic Patient Record-Integrated COPD Self-Management App: The My Lung Health Coach Companion. [PDF]

Int J Chron Obstruct Pulmon Dis
Farrer C, Manankil D, Thuringer K, Ahmed K, Man K, Tohob SA, Kouri A.   +6 more
europepmc   +1 more source