Results 121 to 130 of about 7,151,309 (300)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Perceptions and practices of Swedish wild boar hunters in relation to African swine fever before the first outbreak in Sweden

open access: yesBMC Veterinary Research
Background The first outbreak of African Swine Fever (ASF) in Sweden was detected in 2023 in wild boar. This study was conducted before the first ASF outbreak with the objective of investigating Swedish hunters’ perceptions and practices pertaining to ...
Erika Chenais   +6 more
doaj   +1 more source

Focus control of wide-angle metalens based on digitally encoded metasurface

open access: yesOpto-Electronic Advances
Based on the principle of super-symmetric lens with quadratic phase gradient transformation, combined with the principle of digital coding of metasurface, we propose a wide-angle coded metalens for focusing control in two-dimensional space. This metalens
Yi Chen   +9 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Hall Effect Focus Control System for Vacuum-Membrane Solar Dish Facets

open access: yesSolarPACES Conference Proceedings
This study investigates the development and implementation of a novel Hall effect focus control system for sensing and maintaining membrane displacement of vacuum-membrane solar dish facets for small-scale concentrating solar power (CSP) systems. Such a
Duncan McGee   +2 more
doaj   +1 more source

Comparison of Attention Control and Distraction between Students with and without Learning Impairment [PDF]

open access: yesRavānshināsī-i Afrād-i Istis̠nāyī, 2014
Attention deficit is one of the core elements of learning disorder. Aimed at studying attention deficit, this paper compares attention control and distraction in students with and without learning impairments.
Sajad Basharpoor
doaj  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The effects of time and money scarcity on regulatory focus: The mediating role of sense of control

open access: yesActa Psychologica
Regulatory focus involves two motivational systems: the promotion focus, aimed at achieving positive outcomes through proactive behaviors, and the prevention focus, centered on avoiding negative outcomes.
Yifang Wu   +3 more
doaj   +1 more source

Integrated design and control with a focus on control structures

open access: yes, 2012
The common practice is to design chemical processes and their control systems in sequence. However, process design and control share important decisions, and when the process design is fixed there is little room left to improve the control performance. These observations suggest process design and control should be integrated.
openaire   +4 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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