Results 141 to 150 of about 2,199,799 (303)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Understanding dentists' antibiotic prescribing behaviour in Spain: a focus group study. [PDF]

JAC Antimicrob Resist
Vázquez-Cancela O, Zapata-Cachafeiro M, Figueiras A, Rodríguez-Fernández A.   +3 more
europepmc   +1 more source

What Do Faculty Want?: a Focus Group Study of Faculty at a Mid-sized Public University

, 2006
Michael A. Weber, Robert Flatley
openalex   +1 more source

Guiding Questions for Focus Group Discussions on Health Care, Tuberculosis, and Acceptability of a New TB Vaccine among Incarcerated Individuals.

Mariana Cristina Campos Falleiros Pires (22857465), Yiran E. Liu (11450473), Everton Ferreira Lemos (11450476), Liliane Ferreira da Silva (9530180), Mariana Garcia Croda (11246224), Monica Magalhães (22857468), Dhélio Batista Pereira (7028753), Mariana Pinheiro Alves Vasconcelos (22857471), Rosilene Ruffato (3425549), Solana Monteiro Batista (22857474), Giselle Lima de Freitas (22857477), Marcelo Cordeiro-Santos (671984), Giane Zupellari dos Santos-Melo (22857480), Jair dos Santos Pinheiro (2224042), Lara B. O. Assis (22857483), Lia Gonçalves Possuelo (7394276), Tiago Antonio Heringer (22857486), Daiane Kist Back (22857489), Pauline Schwarzbold (14005795), Jason R. Andrews (7871738), Crhistinne Cavalheiro Maymone Gonçalves (10401861), Julio Croda (230548)   +21 more
openalex   +1 more source

Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidance from Regulatory Agencies: Focus on Downregulation, CYP2C Induction, and CYP2B6 Positive Control [PDF]

, 2017
Niresh Hariparsad, Diane Ramsden, Jairam Palamanda, Joshua G. DeKeyser, Odette A. Fahmi, Jane R. Kenny, Heidi J. Einolf, Michael A. Mohutsky, Magalie Pardon, Y. Amy Siu, Liangfu Chen, Michael Sinz, Barry Jones, Robert L. Walsky, Shannon Dallas, Suresh K. Balani, George Zhang, David B. Buckley, Donald Tweedie   +18 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Empowering future nurses: a focus group study on simulation for transition to clinical practice. [PDF]

BMC Nurs
Haddeland K, Briseid HS, Kaldheim HKA, Johnsen HM.   +3 more
europepmc   +1 more source

Facilitators and barriers of empathetic behaviour in physiotherapy clinical practice: A qualitative focus group study

Konstantina Savvoulidou, Alexia Papageorgiou, Ourania Kolokotroni, Panagiota Kapreli, Aristi Tsokani, Νικόλαος Στριμπάκος, Eleni Kapreli   +6 more
openalex   +2 more sources

Farmers’ economic perceptions of demonstration plot development of kaliandra (Calliandra calothyrsus Meisner) biomass energy at Parungpanjang research forest: findings from a focus group discussion

, 2020
Kresno Agus Hendarto, Desmiwati Desmiwati, Danu Danu Danu, Dida Syamsuwida, Naning Yuniarti, Nurhafifah Siregar, Aam Aminah, Y M M A Nugraheni, Deddy Dwi Nur Cahyono, Arief Hidayat   +9 more
openalex   +1 more source

The Effect of Focused Group Discussion to Enhance Students’ Understanding on Premarital Sexual Behavior Risks

, 2021
Annisa Arrumaisyah Daulay, Syawaluddin Nasution   +1 more
openalex   +2 more sources