Results 231 to 240 of about 2,199,799 (303)

European perspectives on pre-hospital interagency collaboration during terrorist incidents: a focus group study. [PDF]

Scand J Trauma Resusc Emerg Med
Raub D, Bentele M, Robinson Y.
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

Design Guidelines for a Game-Based Physical Rehabilitation System: Focus Group Study.

JMIR Hum Factors
S Elaklouk AM, Ramli RZ, M Alakklouk SM, Rahim N.   +3 more
europepmc   +1 more source

Educational escape game in emergency medicine: what criteria are needed to increase satisfaction: a focus group study. [PDF]

BMC Med Educ
Freyer AC, Bosio A, Laudren G, Goetz C, Pelaccia T, Abensur Vuillaume L.   +5 more
europepmc   +1 more source

Nurse educators' experience of studying while working full-time at a public nursing education institution in South Africa: a focus group study. [PDF]

BMC Nurs
van Rooyen FC, Plessis ED, van Graan AC.
europepmc   +1 more source

Registered Nurses´ Experiences of Caring for Patients with Hypoactive Delirium After Cardiac Surgery - A Qualitative Focus Group Study

Ann Hallberg Kristensen, Carolin Nymark, Malin Stenman, Anna Falk   +3 more
openalex   +1 more source

Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study. [PDF]

Basic Clin Pharmacol Toxicol
Bouarfa S, Göttgens W, Ligthart SA, Maarsingh OR, Vinkers CH, Ruhé HG, Bet PM, Hugtenburg JG.   +7 more
europepmc   +1 more source