Results 91 to 100 of about 7,907,205 (365)

Multiple field-of-view MCAO for a Large Solar Telescope: LOST simulations

, 2010
In the framework of a 4m class Solar Telescope we studied the performance of the MCAO using the LOST simulation package. In particular, in this work we focus on two different methods to reduce the time delay error which is particularly critical in solar ...
Berrilli, Francesco, Del Moro, Dario, Piazzesi, Roberto, Stangalini, Marco   +3 more
core   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Metalens-Based Miniaturized Optical Systems

Micromachines, 2019
Metasurfaces have been studied and widely applied to optical systems. A metasurface-based flat lens (metalens) holds promise in wave-front engineering for multiple applications.
Bo Li, Wibool Piyawattanametha, Zhen Qiu
doaj   +1 more source

Extended depth of focus adaptive optics spectral domain optical coherence tomography

Biomedical Optics Express, 2012
We present an adaptive optics spectral domain optical coherence tomography (AO-SDOCT) with a long focal range by active phase modulation of the pupil. A long focal range is achieved by introducing AO-controlled third-order spherical aberration (SA).
Kazuhiro Sasaki, K. Kurokawa, S. Makita, Y. Yasuno   +3 more
semanticscholar   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Development of Focusing Plasma Mirrors for Ultraintense Laser-Driven Particle and Radiation Sources

Quantum Beam Science, 2018
Increasing the peak intensity to which high power laser pulses are focused can open up new regimes of laser-plasma interactions, resulting in the acceleration of ions to higher energies and more efficient generation of energetic photons.
Robbie Wilson, Martin King, Ross J. Gray, David C. Carroll, Rachel J. Dance, Nicholas M. H. Butler, Chris Armstrong, Steve J. Hawkes, Robert J. Clarke, David J. Robertson, Cyril Bourgenot, David Neely, Paul McKenna   +12 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Grazing-Incidence Neutron Optics based on Wolter Geometries [PDF]

, 2008
The feasibility of grazing-incidence neutron imaging optics based on the Wolter geometries have been successfully demonstrated. Biological microscopy, neutron radiography, medical imaging, neutron crystallography and boron neutron capture therapy would ...
Gubarev, M. V., Mildner, D. F. R., Ramsey, B. D.   +2 more
core   +1 more source

Quantum optics and frontiers of physics: The third quantum revolution

, 2016
The year 2015 was the International Year of Light. It marked, however, also the 20th anniversary of the first observation of Bose-Einstein condensation in atomic vapors by Eric Cornell, Carl Wieman and Wolfgang Ketterle.
Ahufinger, Veronica, Celi, Alessio, Lewenstein, Maciej, Sanpera, Anna   +3 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source