Results 91 to 100 of about 351,194 (295)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Design, Analysis, and Manufacturing of Diffractive Achromatic Optical Systems

Micromachines
The increasing resolution requirements of imaging optical systems must be satisfied by expanding the aperture of the optical system according to Rayleigh’s criterion, and larger apertures of conventional refractive/reflective optics place a greater ...
Yidi Zheng, Junfeng Du, Boping Lei, Jiang Bian, Lihua Wang, Bin Fan   +5 more
doaj   +1 more source

Extended Dual-Focus Microscopy for Ratiometric-Based 3D Movement Tracking

Applied Sciences, 2020
Imaging the three-dimensional movement of small organelles in living cells can provide key information for the dynamics of drug delivery and virus transmission in biomedical disciplines.
Seohyun Lee, Hyuno Kim, Hideo Higuchi
doaj   +1 more source

Focus on Cloaking and Transformation Optics

New Journal of Physics, 2008
'Any sufficiently advanced technology is indistinguishable from magic', as the late Arthur C Clarke wrote. So what does it take to do magic by technology? Transformation optics has developed some tantalizing ideas and the first practical demonstrations of 'pure and applied magic'. Transformation optics gathers an unusual mix of scientists, ranging from
Ulf Leonhardt, David R Smith
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Wavefront analysis and phase correctors design using SHADOW

Journal of Synchrotron Radiation
Knife-edge imaging is a successful method for determining the wavefront distortion of focusing optics such as Kirkpatrick–Baez mirrors or compound refractive lenses.
Hossein Khosroabadi, David Laundy, Vishal Dhamgaye, Kawal Sawhney   +3 more
doaj   +1 more source

On optical forces in spherical whispering gallery mode resonators

, 2011
In this paper we discuss the force exerted by the field of an optical cavity on a polarizable dipole. We show that the modification of the cavity modes due to interaction with the dipole significantly alters the properties of the force.
Anetsberger, Arcizet, Arnold, Ashkin, Ashkin, Barker, Chang, Chen, Deych, Groeblacher, Hu, J. T. Rubin, Jayich, Kippenberg, L. Deych, Li, Nieto-Vesperinas, Romero-Isart, Romero-Isart, Rubin, Rubin, Schliesser, Schliesser, Schliesser, Schulze, Wilson, Wong, Yin   +27 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Models of wave-function collapse, underlying theories, and experimental tests

, 2012
We describe the state of the art in preparing, manipulating and detecting coherent molecular matter. We focus on experimental methods for handling the quantum motion of compound systems from diatomic molecules to clusters or biomolecules.Molecular ...
Adler, S. L., Albert, D., Allen, L., Angelo Bassi, Arndt, M., Ashkin, A., Bell, J. S., Bell, J. S., Bell, J. S., Bohm, D., Breuer, H.-P., Bub, J., Christian, J., Deutsch, D., DeWitt, D. S., Dürr, D., Dürr, D., Feynman, R. P., Frenkel, A., Frenkel, A., Frenkel, A., Ghirardi, G., Ghirardi, G. C., Gikhman, I. I., Gisin, N., Goldin, G. A., Griffiths, R. B., Grishchuk, L. P., Hendrik Ulbricht, Holland, P. R., Joos, E., Karolyhazy, F., Karolyhazy, F., Karolyhazy, F., Karolyhazy, F., Karolyhazy, F., Kinjalk Lochan, Landau, L. D., Lyth, D. H., Maudlin, T., Myrvold, W. C., Omnès, R., Omnès, R., Pearle, P., Pearle, P., Pearle, P., Percival, I. C., Rauch, H., Schilpp, P. A., Schlosshauer, M., Seema Satin, Singh, T. P., Tejinder P. Singh, von Neumann, J., Wheeler, J. A.   +54 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source