Results 141 to 150 of about 350,975 (342)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Scattering Polarimetry in the Hard X-ray Range

Instruments
In one and a half years, the Imaging X-ray Polarimetry Explorer has demonstrated the role and the potentiality of Polarimetry in X-ray Astronomy. The next steps include extension to higher energies.
Enrico Costa
doaj   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

From a Geometry of Vision to a Geometry of Light in Early-Modern Perspective

Architecture_MPS, 2017
Must the architect or artist understand how the world is perceived on the convex surface of the eye to simulate the three-dimensional world on a two-dimensional plane?
doaj   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Wave optical simulations for x-ray nano-focusing optics

, 2012
Markus Osterhoff
openalex   +1 more source

Media 5: Focus issue introduction: nonlinear optics

, 2011
Benoît Boulanger, Steven T. Cundiff, Daniel J. Gauthier, Magnus Karlsson, Yan-qing Lu, Robert A. Norwood, Dmitry V. Skryabin, Takunori Taira   +7 more
openalex   +2 more sources

Nested mirror optics for neutron extraction, transport, and focusing [PDF]

, 2022
Christoph Herb, O. Zimmer, R. Georgii, P. Böni   +3 more
openalex   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

FY06 LDRD Final Report Next-generation x-ray optics: focusing hard x-rays

, 2007
M. J. Pivovaroff, Regina Soufli
openalex   +2 more sources