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The use of point-of-care ultrasound of the heart is becoming more widespread. A variety of users have joined traditional users of cardiac ultrasound, cardiologists, and are imaging their patients in real time at the point of care. Patients with undifferentiated shock, hypotension, chest pain, or dyspnea are ideal candidates for focused cardiac ...
Phillip Andrus, Anthony J. Dean
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Focused Ultrasound Surgery of the Brain [PDF]
Transcranial magnetic resonance imaging guided focused ultrasound surgery (tcMRIgFUS) has recently taken root as a novel, noninvasive alternative to traditional neurosurgery. The ability to treat a variety of neurological diseases by precisely focusing ultrasound energy to a desired target deep inside the brain while leaving collateral structures ...
Martin, Ernst, Werner, Beat
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Focused ultrasound-mediated brain genome editing. [PDF]
Gene editing in the brain has been challenging because of the restricted transport imposed by the blood-brain barrier (BBB). Current approaches mainly rely on local injection to bypass the BBB.
Bechtel, Lawrence+22 more
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Focused Ultrasound for Neuromodulation [PDF]
For more than 70 years, the promise of noninvasive neuromodulation using focused ultrasound has been growing while diagnostic ultrasound established itself as a foundation of clinical imaging. Significant technical challenges have been overcome to allow transcranial focused ultrasound to deliver spatially restricted energy into the nervous system at a ...
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Focused ultrasound for treatment of peripheral brain tumors [PDF]
Malignant brain tumors are the leading cause of cancer-related death in children and remain a significant cause of morbidity and mortality throughout all demographics.
Phillip Mitchell Johansen+5 more
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An Experimental Study on the Heat Enhancement and the Bio-Heat Transfer Using Gold Macro Road and Ultrasound: A Potential Alternative to Kill Cancer Cells [PDF]
We have previously proposed a method of treating solid tumors with a combination of gold macro-rods irradiated with ultrasound. Macro particle sized rods offer a greater circumferential treatment area over nanoparticle options.
Austerlitz, C.+3 more
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Effective chemotherapy delivery for glioblastoma multiforme (GBM) is limited by drug transport across the blood–brain barrier and poor efficacy of single agents.
Tao Sun+13 more
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Focused ultrasound and immunotherapy [PDF]
Thermal therapy has tremendous potential to augment the benefits of immunotherapy. The ability of heat to stimulate both general and tumor specific responses, in part through heat shock protein mediated mechanisms has been known for over two decades.
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Background Chronic back pain due to facet related degenerative changes affects 4-6 million patients a year in the United States. Patients refractory to conservative therapy may warrant targeted injections of steroids into the joint or percutaneous medial
J. Chen+7 more
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MRI-Guided Focused Ultrasound in Cervical Dystonia [PDF]
Introduction. MRI-guided focused ultrasound (MRgFUS) is approved for management of various movement disorders, primarily essential tremor and Parkinson’s disease (PD), with favorable long-term outcomes in numerous patients worldwide.
Rezida M. Galimova+8 more
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