Results 71 to 80 of about 8,775,802 (328)

Ultrasound by emergency physicians to detect abdominal aortic aneurysms: a UK case series [PDF]

, 2004
Early identification of abdominal aortic aneurysms in some patients can be difficult and the diagnosis is missed in up to 30% of patients. Ultrasound cannot be used to identify a leak, but the presence of an aneurysm in an unstable patient is ...
Brenchley, J., Lalanda, M., Sloan, J.P., Venables, H., Walker, A.   +4 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Noninvasive hippocampal blood−brain barrier opening in Alzheimer’s disease with focused ultrasound

Proceedings of the National Academy of Sciences of the United States of America, 2020
The blood–brain barrier (BBB) presents a significant challenge for treating brain disorders. The hippocampus is a key target for novel therapeutics, playing an important role in Alzheimer’s disease (AD), epilepsy, and depression. Preclinical studies have
A. Rezai, M. Ranjan, Pierre F D'Haese, Pierre F D'Haese, M. Haut, J. Carpenter, U. Najib, R. Mehta, J. L. Chazen, Z. Zibly, J. R. Yates, S. Hodder, M. Kaplitt   +12 more
semanticscholar   +1 more source

Focused Ultrasound in Neuroscience. State of the Art and Future Perspectives

Brain Science, 2021
Transcranial MR-guided Focused ultrasound (tcMRgFUS) is a surgical procedure that adopts focused ultrasounds beam towards a specific therapeutic target through the intact skull.
G. Giammalva, C. Gagliardo, Salvatore Marrone, F. Paolini, R. Gerardi, G. Umana, Kaan Yağmurlu, B. Chaurasia, G. Scalia, F. Midiri, L. La Grutta, L. Basile, C. Gulì, D. Messina, M. Pino, F. Graziano, Silvana Tumbiolo, D. Iacopino, R. Maugeri   +18 more
semanticscholar   +1 more source

Sub-ablative thermo-stimulation with high-intensity focused ultrasound targeting the nucleus accumbens for severe alcohol use disorder: a feasibility study

Interdisciplinary Neurosurgery
Ablative neurosurgical approaches targeting the nucleus accumbens (NAc) have been explored for treating substance use disorders, including alcohol use disorder (AUD).
Kun-Hong Li, Wei-Chun Chen, Pei-Han Wu, Wei-Chieh Chang   +3 more
doaj   +1 more source

Effects of Low Intensity Focused Ultrasound on Liposomes Containing Channel proteins. [PDF]

, 2018
The ability to reversibly and non-invasively modulate region-specific brain activity in vivo suggests Low Intensity Focused Ultrasound (LIFU) as potential therapeutics for neurological dysfunctions such as epilepsy and Parkinson's disease.
Babakhanian, Meghedi, Blount, Paul, Boodaghians, Lilian, Grundfest, Warren, Nowroozi, Bryan, Saddik, George, Yang, Limin   +6 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Outcomes and Prognostic Factors of Magnetic Resonance-guided Focused Ultrasound Thalamotomy for Essential Tremor at 2-year Follow-up

Neurologia Medico-Chirurgica
Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is an effective treatment for essential tremor (ET). However, its long-term outcomes and prognostic factors remain unclear. This study aimed to retrospectively investigate 38 patients with
Miki HASHIDA, Satoshi MAESAWA, Sachiko KATO, Daisuke NAKATSUBO, Takahiko TSUGAWA, Jun TORII, Takafumi TANEI, Tomotaka ISHIZAKI, Manabu MUTOH, Yoshiki ITO, Takashi TSUBOI, Satomi MIZUNO, Masashi SUZUKI, Toshihiko WAKABAYASHI, Masahisa KATSUNO, Ryuta SAITO   +15 more
doaj   +1 more source

Rendering volumetric haptic shapes in mid-air using ultrasound:Proceedings of ACM SIGGRAPH Asia 2014 [PDF]

, 2014
We present a method for creating three-dimensional haptic shapes in mid-air using focused ultrasound. This approach applies the principles of acoustic radiation force, whereby the non-linear effects of sound produce forces on the skin which are strong ...
Carter, Tom, Long, Benjamin, Seah, Sue Ann, Subramanian, Sriram   +3 more
core   +2 more sources