Transcranial focused ultrasound stimulation with high spatial resolution [PDF]
Background: Low-intensity transcranial focused ultrasound stimulation is a promising candidate for noninvasive brain stimulation and accurate targeting of brain circuits because of its focusing capability and long penetration depth.
Seongyeon Kim +11 more
doaj +5 more sources
Neuronal responses to focused ultrasound are gated by pre-stimulation brain rhythms [PDF]
Background: Owing to its high spatial resolution and penetration depth, transcranial focused ultrasound stimulation (tFUS) is one of the most promising approaches to non-invasive neuromodulation.
Duc T. Nguyen +3 more
doaj +5 more sources
Abstract This research investigates whether ventricular-focused ultrasound stimulation (ventricle-FUS) can serve as an effective control in studies using transcranial FUS, a non-invasive technology for brain modulation. FUS has notable potential for therapeutic applications but requires a robust control to accurately assess its effects.
Cyril Atkinson-Clement +3 more
doaj +4 more sources
Targeted peripheral focused ultrasound stimulation attenuates obesity-induced metabolic and inflammatory dysfunctions [PDF]
Obesity, a growing health concern, is associated with an increased risk of morbidity and mortality. Chronic low-grade inflammation is implicated in obesity-driven metabolic complications.
Tomás S. Huerta +10 more
doaj +2 more sources
Transcranial focused ultrasound stimulation reduces vasogenic edema after middle cerebral artery occlusion in mice [PDF]
Blood-brain barrier (BBB) disruption underlies the vasogenic edema and neuronal cell death induced by acute ischemic stroke. Reducing this disruption has therapeutic potential.
Li-Dong Deng +11 more
doaj +2 more sources
Investigation of displacement of intracranial electrode induced by focused ultrasound stimulation. [PDF]
Transcranial focused ultrasound (tFUS) is an emerging neuromodulation technique to modulate brain activity non-invasively with high spatial specificity and focality. Given the influence of tFUS on brain activity, combining tFUS with multi-channel intracranial electrophysiological recordings enables monitoring of the activity of large populations of ...
Kim MG, Yu K, Niu X, He B.
europepmc +3 more sources
Focused Ultrasound Stimulation as a Neuromodulatory Tool for Parkinson's Disease: A Scoping Review. [PDF]
Non-invasive focused ultrasound stimulation (FUS) is a non-ionising neuromodulatory technique that employs acoustic energy to acutely and reversibly modulate brain activity of deep-brain structures. It is currently being investigated as a potential novel treatment for Parkinson’s disease (PD).
Lee KS +5 more
europepmc +7 more sources
Transcranial focused ultrasound stimulation of cortical and thalamic somatosensory areas in human. [PDF]
The effects of transcranial focused ultrasound (FUS) stimulation of the primary somatosensory cortex and its thalamic projection (i.e., ventral posterolateral nucleus) on the generation of electroencephalographic (EEG) responses were evaluated in healthy human volunteers.
Kim HC, Lee W, Weisholtz DS, Yoo SS.
europepmc +3 more sources
Multiplexing Focused Ultrasound Stimulation with Fluorescence Microscopy. [PDF]
By focusing low-intensity ultrasound pulses that penetrate soft tissues, LIPUS represents a promising biomedical technology to remotely and safely manipulate neural firing, hormonal secretion and genetically-reprogrammed cells. However, the translation of this technology for medical applications is currently hampered by a lack of biophysical mechanisms
Lacroix JJ, Ozkan AD.
europepmc +4 more sources
Transcranial focused ultrasound is an emerging technique for non-invasive neurostimulation. Compared to magnetic or electric non-invasive brain stimulation, this technique has a higher spatial resolution and can reach deep structures.
Lazzaro di Biase +4 more
doaj +3 more sources

