Results 91 to 100 of about 99,743 (309)
Grossesse Abdominale Menée à Terme avec Fœtus Vivant au Bénin
Health Research in AfricaRÉSUMÉ La grossesse abdominale à terme est un type rare de grossesse extra-utérine dont le diagnostic et la prise en charge sont souvent difficiles.
Epiphane Gandaho +5 more
doaj +1 more source
, 2013 A 33 year old primagravida rhesus positive woman was referred to the Emergency Department by her family doctor at 27 weeks gestation. At 25 weeks of gestation, she had been diagnosed with hypertension and was started on labetalol therapy.
Bugeja, Roberta, Galdes, Caroline
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Frontiers in Physiology, 2012 Background: Recent findings strongly promoted the hypothesis that common pelvic gynaecological diseases including endometriosis and ovarian neoplasia may develop de novo from ectopic endometrial-like glands and/or embryonic epithelial remnants. To verify
Jean eBouquet De Joliniere +8 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
REKAYASA PENENTUAN JENIS KELAMIN DALAM KANDUNGAN MENURUT HUKUM ISLAM
Ahkam: Jurnal Ilmu Syariah, 2015 Engineering the Determination of Sex in the Womb According to Islamic Law. Currently, modern science and technology have developed quickly and dynamically.
Muh. Said HM
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Macroscopic Changes in the Human Placenta in Hypertensive Disorders of Pregnancy in Indian Women: A Cross-sectional Study [PDF]
International Journal of Anatomy Radiology and SurgeryIntroduction: Hypertension (HTN) is a common complication in 6-10% of pregnancies and is one of the prime factors for foetal, as well as, maternal fatalities and morbidities.
Gaurav Khastgir +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source