Results 211 to 220 of about 222,091 (247)

Exploring the conformational landscape of adenylate kinase and beyond with protein folding models. [PDF]

Sci Rep
Bhasin A, Delaunay A, Saccon F, Fu Y.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Cache-efficient and vectorized parallel dynamic programming for RNA folding. [PDF]

PLoS One
Gruzewski M, Palkowski M.
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Novel Knotted Solenoid fold with order-shifted coil arrangement leads to nontrivial 3₁ topology. [PDF]

Proc Natl Acad Sci U S A
Sikora M, Mozajew M, Sikorska JA, da Silva FB, Perlinska AP, Kluza A, Niewieczerzal S, Lukaszewicz M, Wielgus-Kutrowska B, Stachurska-Korzeniowska K, Jackson SE, Sulkowska JI.   +11 more
europepmc   +1 more source

Cross-species systems analysis distinguishes inflammatory remodeling from primary mucus secretory failure in inflammatory bowel disease. [PDF]

Front Immunol
Xhumari J, Ojeda A, Akinsuyi OS, Roesch LFW.   +3 more
europepmc   +1 more source

A first-principles quantitative framework for how cohesin regulators shape chromatin loop extrusion. [PDF]

Cell Genom
Huang Z, Liu X, Ding J.
europepmc   +1 more source

Redox regulation of PDE6 and cGMP signaling in diabetic retinal neurodegeneration. [PDF]

Biochem Biophys Rep
Perez-Martinez CJ, Lewis-Luján LM, Cota-Arrayales CA, Guerrero-Magaña DE, Vargas-Durazo JT, Trushin MV, Osadchuk MA, Iloki-Lewis AP, Galvez-Ruiz JC, Iloki-Assanga SB.   +9 more
europepmc   +1 more source

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3D-Printed Synthetic Vocal Fold Models

Journal of Voice, 2021
Synthetic vocal fold (VF) models used for studying the physics of voice production are comprised of silicone and fabricated using traditional casting processes. The purpose of this study was to develop and demonstrate a new method of creating synthetic VF models through 3D printing in order to reduce model fabrication time, increase yield, and lay the ...
Ryan G T, Romero, Mark B, Colton, Scott L, Thomson   +2 more
openaire   +2 more sources

RNA folding: models and perspectives

Current Opinion in Structural Biology, 2003
Intrinsic events during RNA folding include conformational search and metal ion binding. Several experimentally testable models have been proposed to explain how large ribozymes accomplish folding. Future challenges include the validation of these models, and the correlation of experimental results and theoretical simulations.
Tobin R, Sosnick, Tao, Pan
openaire   +2 more sources