Results 21 to 30 of about 271 (70)

Oncogenic H‐Ras Reprograms Madin‐Darby Canine Kidney (MDCK) Cell‐Derived Midbody Remnant Proteome Following Epithelial‐Mesenchymal Transition

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Epithelial‐mesenchymal transition (EMT) is a fundamental, dynamic cellular process involved in embryonic development, metastasis, organ fibrosis, and tissue regeneration. To define the molecular landscape of secreted midbody remnants (MBRs) to the EMT process, a proteome analysis of MBRs released from Madin–Darby canine kidney (MDCK) cells and
Adnan Shafiq   +6 more
wiley   +1 more source

Regularized Single‐Cell Imaging Enables Generalizable AI Models for Stain‐Free Cell Viability Screening

open access: yesSmall Methods, EarlyView.
Recent advances in AI suggest the potential for stain‐free cell viability screening on brightfield microscopy images. However, no model has been reliably generalized across previously unseen cell types and compounds. Here, we show that “regularized imaging” of single cells in nanowells enables training of generalizable AI models for stain‐free ...
Pan Deng   +4 more
wiley   +1 more source

Review of recent trends of advancements in multilevel inverter topologies with reduced power switches and control techniques

open access: yesIET Power Electronics, EarlyView.
Some of the topologies with a fewer number of power switches are reviewed and scrutinized. An extensive analysis of the topologies, control strategy and applications are presented here, suggesting suitable multilevel inverter solutions to the known industrial application or new research.
Anurag Choudhary   +5 more
wiley   +1 more source

Remote Sensing of Endogenous Pigmentation by Inducible Synthetic Circuits in Grasses

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plant synthetic biology holds great promise for engineering plants to meet future demands. Genetic circuits are being designed, built and tested in plants to demonstrate the proof of concept. However, developing these components in monocots, which the world relies on for grain, lags behind dicot models, such as Arabidopsis thaliana and ...
Dong‐Yeon Lee   +13 more
wiley   +1 more source

Enhancing Tolerance to Combined Heat and Drought Stress in Cool‐Season Grain Legumes: Mechanisms, Genetic Insights, and Future Directions

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT The increasing frequency of concurrent heat and drought stress poses a significant challenge to agricultural productivity, particularly for cool‐season grain legumes, including broad bean (Vicia Faba L.), lupin (Lupinus spp.), lentil (Lens culinaris Medik), chickpea (Cicer arietinum L.), grasspea (Lathyrus sativus L.), pea (Pisum sativum L ...
Manu Priya   +2 more
wiley   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng   +15 more
wiley   +1 more source

Signal Processing for the Cluster Wideband Data Burst Mode

open access: yesJournal of Geophysical Research: Space Physics, Volume 131, Issue 2, February 2026.
Abstract The Wideband Data instrument is part of the Cluster spacecraft Wave Experiment Consortium. Its primary data path is a direct connection to the spacecraft data handling system providing real time downlink to the ground stations of the Deep Space Network and Panska Ves Observatory.
K. H. Yearby   +2 more
wiley   +1 more source

Peptide Electrostatic Modulation Directs Human Neural Cell Fate

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos   +10 more
wiley   +1 more source

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early‐Onset Colorectal Cancer

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
This study identifies a unique physical signature of colorectal cancer in younger adults: their tissues are mechanically stiffer than those in older patients with the same cancer. Furthermore, stromal remodeling in early‐onset colorectal cancer promotes epithelial mechanotransduction and proliferation, showing how mechanical alterations in the tissue ...
Nicole C. Huning   +18 more
wiley   +1 more source

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