Results 221 to 230 of about 181,230 (381)

Folic acid supplementation on congenital heart disease and its dual character

Current Research in Pharmacology and Drug Discovery
Pregnant women are vulnerable to folate deficiency as its requirement is substantially greater than folate requirements for non-pregnant women. Folic acid is a synthetic form of folate and has been used in the fortified foods and nutritional supplements.
Yanli Wang, Zhengpei Cheng, Mingfang He, Rui Gu, Harvest F. Gu   +4 more
doaj  

Folate transfer in placental choriocarcinoma cells treated with valproic acid: Insights gained through comparisons with the amide derivative sec‐butylpropylacetamide and its individual stereoisomers

Epilepsia, EarlyView.
Abstract Objective We have previously shown that valproic acid (VPA) alters the expression of placental carriers of essential nutrients, including folates. Here, we exposed a placental cell line to VPA, its central nervous system‐active amide derivative sec‐butylpropylacetamide (SPD), and its individual stereoisomers to address the question of whether ...
Natalia Erenburg, Roa’a Hamed, Alina Nemirovski, Meir Bialer, Sara Eyal   +4 more
wiley   +1 more source

Gingival hyperplasia and folic acid deficiency from anticonvulsive drug therapy A theoretical relationship

, 1977
Richard I. Vogel
openalex   +1 more source

Comprehensive Literature Review Evaluating the Use, Safety, and Efficacy of Subcutaneous Methotrexate in the Treatment of Adult Patients With Moderate‐To‐Severe Plaque‐Type Psoriasis

International Journal of Dermatology, EarlyView.
ABSTRACT Methotrexate (MTX) is a conventional systemic therapy widely used to treat chronic plaque‐type psoriasis, a chronic inflammatory skin disease that significantly impacts patients' quality of life. MTX can be administered orally or subcutaneously. Over the past decades, the use of subcutaneous versus oral MTX has been a subject of ongoing debate
Manuelle Viguier, José‐Manuel Carrascosa‐Carrillo, Pariyawan Rakvit, Maria‐Magdalena Constantin, Alice‐Anaïs Varlet, Solenn Le Clanche, Linda A. W. Verhagen, Wolf‐Henning Boehncke   +7 more
wiley   +1 more source

Folic acid abnormalities in iron deficiency: the mechanism of decreased serum folate levels in rats

, 1974
Phillip P. Toskes, George W. Smith, Thomas A. Bensinger, Ralph A. Giannella, Marcel E. Conrad   +4 more
openalex   +1 more source

The molecular mechanisms of defensive‐grade organic acid biosynthesis in ground beetles

Insect Molecular Biology, EarlyView.
Formic acid and methacrylic acid are the primary defensive chemicals in the pygidial gland secretions of Platynus angustatus and Pterostichus moestus, respectively. Comparative transcriptomics suggests the folate cycle and valine catabolism may be involved in the biosynthesis of formic acid and methacrylic acid, respectively.
Adam M. Rork, Sihang Xu, Athula Attygalle, Tanya Renner   +3 more
wiley   +1 more source

Economic burden of sickle cell disease in Australia

Internal Medicine Journal, EarlyView.
Abstract Background Sickle cell disease (SCD) is an inherited condition that impairs red blood cell function, posing a substantial health burden on patients. As the prevalence of SCD in Australia rises due to migration, discussions surrounding treatment and management strategies are becoming more prominent. Aims Australia lacks a dedicated study on the
Steve Nwokeocha, Helen E. Haysom, Cameron Wellard, Tracy Roberts, Mwayi Kachapila, Melissa Chee, Dennis Petrie, Zoe K. McQuilten, Neil Waters, Anthea Greenway, Kylie Mason, Anna Nelson, Zane Kaplan, P. Joy Ho, Erica M. Wood, Adam Irving, on behalf of the Australian Haemoglobinopathy Registry   +16 more
wiley   +1 more source

Folic acid deficiency enhanced microglial immune response via the Notch1/nuclear factor kappa B p65 pathway in hippocampus following rat brain I/R injury and BV2 cells. [PDF]

J Cell Mol Med, 2019
Cheng M, Yang L, Dong Z, Wang M, Sun Y, Liu H, Wang X, Sai N, Huang G, Zhang X.   +9 more
europepmc   +1 more source

European Guideline (EuroGuiDerm) on atopic eczema: Living update

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg, M. Kinberger, B. Arents, N. Aszodi, S. Barbarot, T. Bieber, H. A. Brough, P. Calzavara‐Pinton, S. Christen‐Zaech, M. Deleuran, M. Dittmann, N. Fosse, K. Gáspár, L. A. A. Gerbens, U. Gieler, G. Girolomoni, S. Gregoriou, S. Holland, C. G. Mortz, A. Nast, U. Nygaard, E. M. Rehbinder, J. Ring, M. Rossi, E. Serra‐Baldrich, D. Simon, Z. Z. Szalai, J. C. Szepietowski, A. Torrelo, T. Werfel, R. N. Werner, C. Flohr   +31 more
wiley   +1 more source

Acclimation conditions and subsequent acute hypoxia challenges do not affect the frequency of erythrocyte nuclear segmentation in triploid brook charr Salvelinus fontinalis (Mitchill 1814)

Journal of Fish Biology, EarlyView.
Abstract Routine observations of blood smears have repeatedly shown that triploid fish have a greater proportion of erythrocytes with nuclear segmentation (ENS) than diploids; however, there is as yet no understanding of why this is the case and whether it affects erythrocyte function.
John D. Clark, Christopher A. Baker, Sarah A. McGeachy, Rebecca R. Jensen, Tillmann J. Benfey   +4 more
wiley   +1 more source