Results 71 to 80 of about 408,258 (430)

In vitro follicle growth supports human oocyte meiotic maturation

open access: yesScientific Reports, 2015
In vitro follicle growth is a potential approach to preserve fertility for young women who are facing a risk of premature ovarian failure (POF) caused by radiation or chemotherapy.
Shuo Xiao   +5 more
semanticscholar   +1 more source

Follicle-stimulating hormone receptor: Advances and remaining challenges [PDF]

open access: yesIn: Arun K. Shukla (ed.), dir., G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation Part A (p. 1-58). International Review of Cell and Molecular Biology, 338 (1\`ere ed.). USA : Elsevier. 171 p. (2018), 2018
Follicle-stimulating hormone (FSH) is produced in the pituitary and is essential for reproduction. It specifically binds to a membrane receptor (FSHR) expressed in somatic cells of the gonads. The FSH/FSHR system presents many peculiarities compared to classical G protein-coupled receptors (GPCRs).
arxiv   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Concentrações hormonais e desenvolvimento folicular de vacas leiteiras em hipertermia sazonal e aguda Hormone concentration and follicular development in dairy cows under seasonal and acute hyperthermia

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2006
Avaliaram-se as concentrações hormonais e os parâmetros de desenvolvimento folicular de vacas leiteiras expostas ao calor sazonal e agudo. Dividiram-se os animais em quatro grupos: verão (n=5), outono (n=5), inverno com hipertermia aguda (grupo câmara ...
B.J. Lew, R. Meidan, D. Wolfenson
doaj   +1 more source

A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function

open access: yesFrontiers in Cell and Developmental Biology, 2021
The two homologous estrogen receptors ERα and ERβ exert distinct effects on their cognate tissues. Previous work from our laboratory identified an ERβ-specific phosphotyrosine residue that regulates ERβ transcriptional activity and antitumor function in ...
Bin Yuan   +4 more
doaj   +1 more source

Anti-Müllerian hormone promotes pre-antral follicle growth, but inhibits antral follicle maturation and dominant follicle selection in primates.

open access: yesHuman Reproduction, 2016
STUDY QUESTION What are the direct effects and physiological role of anti-Müllerian hormone (AMH) during primate follicular development and function at specific stages of folliculogenesis?
Jing Xu   +4 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Effects of photoperiod on performance, ovarian morphology, reproductive hormone level, and hormone receptor mRNA expression in laying ducks

open access: yesPoultry Science, 2021
We investigated the effect of photoperiod on performance, ovarian morphology, reproductive hormones levels, and their receptors mRNA expressions in laying ducks.
Yao-ming Cui   +4 more
doaj  

RFRP3 influences basal lamina degradation, cellular death, and progesterone secretion in cultured preantral ovarian follicles from the domestic cat. [PDF]

open access: yes, 2019
The hypothalamic neuropeptide RFRP3 can suppress hypothalamic GnRH neuron activation and inhibit gonadotropin release from the anterior pituitary. RFRP3 is also produced locally in the ovary and can inhibit steroidogenesis and follicle development in ...
Bentley, George   +2 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

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