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Genetic Abnormalities in Follicular Lymphoma and Transformed Follicular Lymphoma.
Blood, 2012Abstract Abstract 2648 Follicular lymphoma (FL) is an indolent lymphoma and the second most common type of non-Hodgkin lymphoma in the Western world. It is characterized by the t(14;18) chromosomal translocation, which is present in up to 90% of cases.
Wright, George W +22 more
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The curability of follicular lymphoma
Transfusion and Apheresis Science, 2007Follicular lymphoma has been widely thought to be an incurable disease. However, if cure is defined as a remission that continues indefinitely and the patient eventually dies of another disease, some patients with follicular lymphoma are cured. Follicular lymphoma grade 3 acts much like diffuse large B-cell lymphoma, and cure is frequent.
Matthew, Lunning, James O, Armitage
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Treatment of follicular lymphoma
Current Opinion in Oncology, 1998Follicular lymphoma is one of the most common neoplastic lymphoproliferative diseases encountered in the western world. Intensive scientific scrutiny has led to detailed understanding of the nature of the malignant cell and the specific genetic abnormalities which are frequently encountered and likely to be etiologic.
J M, Connors, R, Klasa
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Obinutuzumab in follicular lymphoma
Drugs of Today, 2016The CD20 marker continues to be exploited as a therapeutic target for non-Hodgkin's lymphoma. Obinutuzumab is part of a new generation of anti-CD20 monoclonal antibodies, which are synthesized using molecular engineering technology, resulting in novel target epitopes and unprecedented optimization of antibody-dependent cellular cytotoxicity and ...
Martinez-Calle, N. (Nicolas) +4 more
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Hematological Oncology, 2023
AbstractThe past two decades have seen remarkable progress in both biological understanding and optimizing treatment of follicular lymphoma. Historically considered an incurable disease, long‐term follow‐up of several induction approaches demonstrates that up to 40% of patients enjoy remission durations of 10 or more years, and risk of dying of ...
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AbstractThe past two decades have seen remarkable progress in both biological understanding and optimizing treatment of follicular lymphoma. Historically considered an incurable disease, long‐term follow‐up of several induction approaches demonstrates that up to 40% of patients enjoy remission durations of 10 or more years, and risk of dying of ...
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2021
Follicular lymphoma (FL) is an indolent yet challenging disease. Despite a generally favorable response to immunochemotherapy regimens, a fraction of patients does not respond or relapses early with unfavorable prognosis. For the vast majority of those who initially respond, relapses will repeatedly occur with increasing refractoriness to available ...
Milpied, Pierre +6 more
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Follicular lymphoma (FL) is an indolent yet challenging disease. Despite a generally favorable response to immunochemotherapy regimens, a fraction of patients does not respond or relapses early with unfavorable prognosis. For the vast majority of those who initially respond, relapses will repeatedly occur with increasing refractoriness to available ...
Milpied, Pierre +6 more
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Radioimmunotherapy in follicular lymphoma
Best Practice & Research Clinical Haematology, 2011The exquisite sensitivity of haematological malignancies to targeted radiation make Radioimmunotherapy (RIT) a theoretically attractive therapeutic approach. Furthermore, impressive results initially achieved by the pioneers in this field and more recently in larger studies have demonstrated the high clinical activity of RIT in follicular NHL (FL). For
Illidge, Tim; id_orcid 0000-0003-3191-7324 +1 more
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Prognosis of follicular lymphomas
Hematological Oncology, 2006AbstractFollicular lymphoma (FL) is as an indolent neoplasia with median survival measured in decades. Nevertheless, some patients have poor progression‐free survival and overall survival. Several treatment approaches are proposed for patients with FL, however criteria to rationalize treatment decisions are lacking. Studies have been performed to build
LUMINARI, Stefano, FEDERICO, Massimo
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The American Journal of Surgical Pathology, 1986
Fifteen cases of cutaneous follicular lymphoma were evaluated clinically, histologically, and immunologically. Nine of the patients presented with skin disease alone, which showed a predilection for the scalp and forehead. The six remaining cases had either concurrent or secondary cutaneous involvement.
C F, Garcia +3 more
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Fifteen cases of cutaneous follicular lymphoma were evaluated clinically, histologically, and immunologically. Nine of the patients presented with skin disease alone, which showed a predilection for the scalp and forehead. The six remaining cases had either concurrent or secondary cutaneous involvement.
C F, Garcia +3 more
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Management of follicular lymphoma
Current Opinion in Oncology, 1994Despite the fact that a small proportion of patients with follicular lymphoma may be alive 20 years after the initial diagnosis, and that it is repeatedly, albeit usually only partially, responsive to relatively mild therapy, the disease remains stubbornly incurable for the majority.
A, Rohatiner, T A, Lister
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