S-Geranylgeranyl-L-glutathione is a ligand for human B cell-confinement receptor P2RY8. [PDF]
, 2019 Germinal centres are important sites for antibody diversification and affinity maturation, and are also a common origin of B cell malignancies. Despite being made up of motile cells, germinal centres are tightly confined within B cell follicles. The cues
Cyster, Jason G +4 more
core +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
EndocrinesBackground: Combined oral contraceptives (COCs) work mostly by preventing the pre-ovulatory gonadotropin surge, but the action of COCs on spontaneous episodic and GnRH (gonadotropin-releasing hormone)-induced LH (luteinizing hormone) release has been ...
Alessandro D. Genazzani +7 more
doaj +1 more source
Live Birth Outcomes for PCOS Patients Under the Follicular-Phase Long-Acting GnRH Agonist Protocol or Antagonist Protocol - A Retrospective Chinese Cohort. [PDF]
J Multidiscip Healthc, 2023 Zhai J +7 more
europepmc +1 more source
Immunoreactive inhibin in human follicular fluid in an ovarian hyperstimulation proramme for in vitro fertilisation: correlations and different forms [PDF]
, 1993 Lechner, K. +5 more
core +1 more source
Menstrual cycle and competitive bidding [PDF]
In an experiment using two-bidder first-price sealed bid auctions with symmetric independent private values, we collected information on the female participants' menstrual cycles.
Pearson, Matthew, Schipper, Burkhard C
core +1 more source
Effect of Estrogen on Musculoskeletal Performance and Injury Risk. [PDF]
, 2018 Estrogen has a dramatic effect on musculoskeletal function. Beyond the known relationship between estrogen and bone, it directly affects the structure and function of other musculoskeletal tissues such as muscle, tendon, and ligament.
Baar, Keith, Chidi-Ogbolu, Nkechinyere
core
Advanced Science, EarlyView.The integrated system, comprising bacterial‐targeted photothermal nanoparticles (Fe2O3‐CS@RBP) and multifunctional hydrogels (PAOC‐3@BA) modules, achieves rapid wound healing within one week. This work introduces a smart therapeutic platform that integrates bacterial targeting, self‐regulating photothermal therapy, tissue adhesion, and stimulus ...
Hongping Wan, Huirong Tan, Xinghong Zhao
wiley +1 more source
GnRH-agonist implants suppress reproductive function and affects ovarian LHR and FSHR expression in prepubertal female cats [PDF]
, 2017 Axner +34 more
core +2 more sources
Advanced Science, EarlyView.A multifunctional vascular bed platform is created using coaxial 3D printing, allowing the one‐step integration of organoid microspheres with perfusable vascular structures. This strategy enables rapid and functional vascularization of organoids to support tissue repair and vascularization, providing a scalable and translationally promising approach ...
Kunrui Wang +10 more
wiley +1 more source