Results 151 to 160 of about 9,648,802 (292)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Inconsistent responses in the dichotomous choice contingent valuation with follow-up questions

This essay develops a new method to diagnose inconsistency in dichotomous choice contingent valuation with follow-up questions: in particular, downward bias in the mean WTP.
Haab, Timothy C., Kang, Heechan
core  

Recommendations for Living Kidney Donor Follow-Up in Canada. [PDF]

Clin Transplant
Singh SK, Jaure A, Gill MP, Johnston O, Gill J, Caton N, Pâquet M, John P, Ogniben A, Chritchley S, Dipchand C, Gill J, Pike P, Shamseddin MK, Bau J, Gourishankar S, Lesage J, Mainra R, Yohanna S, Connaughton DM, Gogan N, Storsley L, Redditt V, Duff M, Cazzolli R, Dominello A, Silva JR, Scholes-Robertson N, Sinka V, Gill JS.   +29 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Anatomy of a Cohort: 40-Year Follow-Up of a Sjögren's Cohort. [PDF]

J Clin Med
Viejo-Sosa B, Couto-Lareo U, Angerri-Nadal M, Isenberg DA.   +3 more
europepmc   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

FEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino, Giuliana Fusco, Alfonso De Simone   +2 more
wiley   +1 more source

Improving Pediatric Follow-Up Documentation Through a Structured Follow-Up Card: A Closed-Loop Quality Improvement Project in Sudan. [PDF]

Cureus
Mohamed BMA, Ibrahim ESA, Siedahmed HNK, Dafalla HMA, Almsbah AAA, Salih AAM, Salman Abdalgani HJ, Murdas SA, Hayo SGD, Suliman Ali NS, Malik RKA, Elmatari SOS, Osman AMA, Fatih W, Mohammed AHEO, Kanan Ahmed AA, Hassan AM, Abdulazeez RA, Mohamed WBS, Albadawy IMAH.   +19 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source