Results 121 to 130 of about 13,859,586 (381)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

One-Year Follow-Up Evaluation of Cognitive Function in Patients with Coronary Artery Disease and Over 65 Years of Age in Isfahan City, Iran

open access: yesمجله دانشکده پزشکی اصفهان, 2017
Background: Vascular diseases and cognitive impairment are prevalent in elder people. Association between cardiovascular diseases and cognitive dysfunction is reported in previous studies and there are limited studies followed patients with ...
Majid Barekatain   +4 more
doaj  

Clinical and Laboratory Predictors of Poor Outcomes in Pediatric Cerebral Malaria in Nigeria

open access: yesOman Medical Journal
Objectives: Cerebral malaria remains poorly understood despite being a common manifestation of severe malaria in children, often associated with poor outcomes. We sought to describe the burden of childhood cerebral malaria and identify factors predictive
Olayinka Rasheed Ibrahim   +3 more
doaj   +1 more source

Maximising follow-up participation rates in a large scale 45 and Up Study in Australia

open access: yesEmerging Themes in Epidemiology, 2016
Background The issue of poor response rates to population surveys has existed for some decades, but few studies have explored methods to improve the response rate in follow-up population cohort studies.
Adrian Bauman   +7 more
doaj   +1 more source

Feasibility of Follow-Up Studies and Reclassification in Spinocerebellar Ataxia Gene Variants of Unknown Significance. [PDF]

open access: yesFront Genet, 2022
Ghorbani F   +13 more
europepmc   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

Investigating Factors Affecting Compliance of Patients Who are Candidates for Non-Surgical Periodontal Treatment Referred to Yazd Faculty of Dentistry in 2023 [PDF]

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Considering the importance of periodontal supportive treatment in long-term preservation of teeth and prevention of recurrence of periodontitis, it was aimed to identify the factors affecting patients' compliance in continuing periodontal ...
Fahimeh Rashidi Maybodi   +2 more
doaj  

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