Results 121 to 130 of about 247,910 (307)

Extending the firm versus industry debate into social enterprises: A multilevel analysis on Spanish cooperatives 2008–2023

open access: yesAnnals of Public and Cooperative Economics, EarlyView.
Abstract An important debate in the field of strategy and industrial organization economics has long focused on whether the industry environment or firm idiosyncrasies have a greater impact on firm performance. However, cooperatives have been excluded from this inquiry, despite profits being the primary means to achieve their social objectives.
Pablo Doucet, Marta Solórzano‐García
wiley   +1 more source

El debate de los fondos estructurales de la Unión Europea y su contribución al despoblamiento rural [PDF]

open access: yes, 2017
Contiene la nota "En la Unión Europea nunca ha habido voluntad real de invertir en desarrollo rural", de Ángel de ...
Grupo Editor de la Revista Soberanía Alimentaria
core  

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

open access: yesBrain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García   +13 more
wiley   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

open access: yesBrain Pathology, EarlyView.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga   +11 more
wiley   +1 more source

Review about Mª Antonia Casanova: The evaluation of basic skills

open access: yesAvances en Supervisión Educativa, 2012
Título: LA EVALUACIÓN DE LAS COMPETENCIAS BÁSICAS Autora: Mª Antonia Casanova Editorial: La Muralla ISBN: 9788471338013 Madrid, 2012. Autor de la reseña:  Milagros Muñoz Martín   Las competencias básicas constituyen la  mayor novedad ...
Milagros Muñoz Martín
doaj  

The L108I polymorphism in mouse prion protein drives spontaneous disease and enhances transmission of atypical and classical prion strains

open access: yesBrain Pathology, EarlyView.
A single amino acid change (L108I) combined with PrP overexpression drives spontaneous atypical prion formation in mice, enabling also efficient propagation of diverse prion strains. This model allows studying how spontaneous prion diseases arise and provides powerful tools for investigating strain emergence, transmission barriers, and mechanisms ...
Hasier Eraña   +20 more
wiley   +1 more source

Improve the relationships between educational research and practice

open access: yesAvances en Supervisión Educativa, 2005
La autora pone de relieve el divorcio existente entre la investigación educativa y la práctica docente, planteando que los investigadores desconocen la realidad de las aulas y los profesores no incorporan a su práctica los avances de la investigación. Un
Mercedes Muñoz-Repiso Izaguirre
doaj  

Synergistic antiviral activity against human adenovirus through combination of itraconazole and brincidofovir

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Human adenovirus (HAdV) causes respiratory or gastrointestinal tract infections depending on the virus subtype. While HAdV infections are generally self‐limiting in immunocompetent people, they can result in significant morbidity and mortality in immunocompromised adults and children.
Mohamed Zamzamy   +16 more
wiley   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert   +13 more
wiley   +1 more source

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