Results 61 to 70 of about 6,471 (161)

Computational Rheo‐Hydrodynamic Analysis of Non‐Newtonian Blood Flow Through a Tilted Ellipsoidal Stenosed Vascular Segment

Engineering Reports, Volume 8, Issue 6, June 2026.
Non‐Newtonian blood flow through multiple tilted ellipsoidal stenoses is numerically investigated using the DeKee‐Turcotte‐Papanastasiou model. The results reveal asymmetric velocity fields, elevated wall shear stress, significant pressure drops, and shear‐dependent thermal effects, highlighting the critical hemodynamic risks associated with eccentric ...
Azad Hussain, Huma Naz
wiley   +1 more source

Adenosine‐Sensitive Focal Atrial Tachycardia Late After Atriopulmonary Connection Fontan Procedure: A Case Report

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
We describe a case of adenosine‐sensitive focal atrial tachycardia (AT) in a patient late after atriopulmonary connection (APC) Fontan procedure. Radiofrequency application successfully abolished the AT; meanwhile, conversion to total cavopulmonary connection (TCPC) and/or Maze procedure may fail to suppress the AT because the origin was crista ...
Takahiko Kinjo, Daiji Takeuchi, Keiko Toyohara, Kei Inai, Morio Shoda   +4 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Diastolic dysfunction in patients with Fontan palliation is associated with death and heart transplantation

Journal of Cardiovascular Magnetic Resonance
: Background: Adults with Fontan failure (FF) have variable presentations and are often diagnosed late. Reliable predictors of FF are unknown. Diastolic dysfunction may be associated with adverse outcomes late after Fontan palliation.
Edward H. Hardison, Christopher C. Henderson, Rachel K. Duncan, Kristen George-Durrett, James C. Slaughter, Ryan D. Byrne, Joshua D. Chew, Benjamin P. Frischhertz, David A. Parra, Angela J. Weingarten, Jonathan H. Soslow, Daniel E. Clark   +11 more
doaj   +1 more source

Association of Fontan Circulation With Gut Microbiome Derived Straight and Branched Short Chain Fatty Acids

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1825-1836, June 2026.
Adults with Fontan circulation (n = 20) and matched controls underwent body composition, frailty testing, CPET, and NICaS hemodynamics. Plasma short‐chain fatty acids were quantified by LC–MS/MS. Fontan patients had higher straight and branched SCFAs, correlating with lower muscle mass, greater frailty, reduced VO2max, and worse resting/postexercise ...
Ashish H. Shah, Yixiu Liu, Heather K. Armstrong, Jun Han, David R. Goodlett, Amir Ravandi, Sanjiv Dhingra   +6 more
wiley   +1 more source

Pediatric heart transplantation after a Fontan procedure

Вестник трансплантологии и искусственных органов
The Fontan procedure is a surgical technique used for hemodynamic correction of complex congenital heart defects (CHDs), and is used when radical correction of CHDs is anatomically impossible.
D. V. Ryabtsev, A. S. Ivanov, M. T. Bekov, E. A. Spirina, V. N. Poptsov, E. S. Kavardakova, A. Ch. Chartaev, S. V. Gautier   +7 more
doaj   +1 more source

Ventricular‐Arterial Function and Coupling in the Adult Fontan Circulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background In adult Fontan patients, ventricular or arterial dysfunction may impact homeostasis of the Fontan circulation and predispose to heart failure. We sought to characterize ventricular‐arterial (VA) properties in adult Fontan patients.
Hirofumi Saiki, Benjamin W. Eidem, Tomohito Ohtani, Martha A. Grogan, Margaret M. Redfield   +4 more
doaj   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, Volume 15, Issue 17, 8 May 2026.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

Advanced Science, Volume 13, Issue 30, 28 May 2026.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab, Mehdi Salar Amoli, Tanmay Mukherjee, Maryam Bagheri, Boeun Hwang, Linqi Jin, Yamini Singh, Sophia Norton, Ashay Vishwas Bongirwar, Shweta Karnik, Lakshmi Prasad Dasi, Reza Avazmohammadi, Rene Romero, Holly D. Bauser‐Heaton, Vahid Serpooshan   +14 more
wiley   +1 more source

Dobutamine stress testing in patients with Fontan circulation augmented by biomechanical modeling.

PLoS ONE, 2020
Understanding (patho)physiological phenomena and mechanisms of failure in patients with Fontan circulation-a surgically established circulation for patients born with a functionally single ventricle-remains challenging due to the complex hemodynamics and
Bram Ruijsink, Konrad Zugaj, James Wong, Kuberan Pushparajah, Tarique Hussain, Philippe Moireau, Reza Razavi, Dominique Chapelle, Radomír Chabiniok   +8 more
doaj   +1 more source