Results 51 to 60 of about 245,722 (287)

The comparison of obese and non-obese persons in terms of food addiction

open access: yesTurkish Journal of Internal Medicine, 2021
Aim: Although the term 'addiction' was previously used only to describe excessive alcohol and substance abuse, it has recently been realized that some behaviors have a neurobiological basis similar to alcohol and substance addiction.
Hasan Hüseyin, Hacer Hicran Mutlu
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

'Maybe they should regulate them quite strictly until they know the true dangers': A focus group study exploring UK adolescents’ views on e-cigarette regulation [PDF]

open access: yes, 2016
Background and aims: Regulation of electronic cigarettes has moved to the top of the addiction policy agenda, as demonstrated by the recent focus across the UK on introducing age of sale restrictions.
Hilton, Shona   +2 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

OBESITY AND NUTRIENT CONSUMPTION: A RATIONAL ADDICTION? [PDF]

open access: yes
This study tests for a rational addiction to food nutrients as a potential explanation for the obesity epidemic. A random coefficients (mixed) logit model applied to household scanner data finds evidence of a strong, forward-looking addiction to ...
Patterson, Paul M.   +2 more
core   +4 more sources

Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake [PDF]

open access: yes, 2006
Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects.
Le Merrer, Julie, Stephens, David N
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants

open access: yesFrontiers in Psychiatry, 2018
Aims: Due to the increasing evidence of shared vulnerabilities between addictive behaviors and excessive food intake, the concept of food addiction in specific clinical populations has become a topic of scientific interest.
Roser Granero   +33 more
doaj   +1 more source

Public views on food addiction and obesity: implications for policy and treatment. [PDF]

open access: yesPLoS ONE, 2013
According to their advocates, neurobiological explanations of overeating, or "food addiction", have the potential to impact public understanding and treatment of obesity.
Natalia M Lee   +5 more
doaj   +1 more source

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