Results 61 to 70 of about 245,280 (285)

Recent updates on incubation of drug craving: a mini-review [PDF]

open access: yes, 2015
Cue-induced drug craving progressively increases after prolonged withdrawal from drug self-administration in laboratory animals, a behavioral phenomenon termed 'incubation of drug craving.' Studies over the years have revealed several important neural ...
Abdolahi   +39 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

"Food addiction" in patients with eating disorders is associated with negative urgency and difficulties to focus on long-term goals

open access: yesFrontiers in Psychology, 2016
Objectives: The present study aimed to investigate if eating disorder patients differ in specific personality traits depending on a positive screening of food addiction and to find a model to predict food addiction in eating disorder patients using ...
Ines eWolz   +20 more
doaj   +1 more source

Role of CB2 cannabinoid receptor in the development of food addiction in male mice

open access: yesNeurobiology of Disease, 2023
The endocannabinoid system plays an important role in multiple behavioral responses due to its wide distribution in the central nervous system. The cannabinoid CB1 receptor was associated to the loss of behavioral control over food intake occurring ...
A. García-Blanco   +6 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants

open access: yesFrontiers in Psychiatry, 2018
Aims: Due to the increasing evidence of shared vulnerabilities between addictive behaviors and excessive food intake, the concept of food addiction in specific clinical populations has become a topic of scientific interest.
Roser Granero   +33 more
doaj   +1 more source

A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction

open access: yesNature Communications, 2020
Food addiction is linked to obesity and eating disorders. In a mouse model of food addiction, the authors show that a medial prefrontal cortex-nucleus accumbens pathway is involved in vulnerability and resilience against the development of food addiction-
Laura Domingo-Rodriguez   +15 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Food Cravings, Appetite, and Snack-Food Consumption in Response to a Psychomotor Stimulant Drug: The Moderating Effect of ‘Food Addiction’

open access: yesFrontiers in Psychology, 2014
There is mounting evidence that many highly processed foods have addictive properties, and that some cases of compulsive overeating are behavioral addictions.
Caroline eDavis   +4 more
doaj   +1 more source

Low control over palatable food intake in rats is associated with habitual behavior and relapse vulnerability: individual differences. [PDF]

open access: yesPLoS ONE, 2013
The worldwide obesity epidemic poses an enormous and growing threat to public health. However, the neurobehavioral mechanisms of overeating and obesity are incompletely understood.
Johannes W de Jong   +3 more
doaj   +1 more source

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