Results 101 to 110 of about 3,258,233 (341)
Arthritis Care &Research, Accepted Article.Objectives Social determinants of health (SDoH) can impact outcomes but are not routinely screened for in US outpatient rheumatology clinics. This study determined the feasibility of routine point‐of‐care SDoH screening among patients with systemic lupus erythematosus (SLE), and associated barriers and facilitators at the physician, care team, and ...
S. Sam Lim +11 more
wiley +1 more source
Drug-Target Interaction/Affinity Prediction: Deep Learning Models and Advances Review [PDF]
arXivDrug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate prediction of how drugs interact with their targets and the development of new drugs by using better methods and ...
arxiv
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
History of veterinary medicine in the Food and Drug Administration [PDF]
, 1991 Orland A. Soave
openalex +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Successes and challenges of PARP inhibitors in cancer therapy
Frontiers in Oncology, 2015 Tiffany K Ricks +6 more
doaj +1 more source
On drug transport after intravenous administration [PDF]
arXiv, 2011 A mathematical model of a drug transport after rapid injection is given. It takes into account three processes: - drug plasma protein binding in central compartment - transport processes between the central compartment and the peripheral compartment - elimination of a drug from the central compartment. .
arxiv
The role of clinical trials in the Food and Drug Administration approval process for cardiovascular devices. [PDF]
, 1994 Wolf Sapirstein +2 more
openalex +1 more source
Advanced Biology, EarlyView.The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua +5 more
wiley +1 more source
Extracting adverse drug reactions and their context using sequence labelling ensembles in TAC2017 [PDF]
Text Analytics Conference 2017, 2019 Adverse drug reactions (ADRs) are unwanted or harmful effects experienced after the administration of a certain drug or a combination of drugs, presenting a challenge for drug development and drug administration. In this paper, we present a set of taggers for extracting adverse drug reactions and related entities, including factors, severity, negations,
arxiv