Results 121 to 130 of about 687,018 (362)

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

open access: yesAdvanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo   +8 more
wiley   +1 more source

Food and Drug Administration [PDF]

open access: yes, 2003
Stacy Lindborg, Susan Ellenberg
openaire   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

open access: yesAdvanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li   +10 more
wiley   +1 more source

Femtosecond Single‐ and Double‐Pulse Fabrication of Periodic Nanostructures on Stainless Steel for Surface‐Enhanced Raman Spectroscopy

open access: yesAdvanced Engineering Materials, EarlyView.
Periodic submicron features are fabricated on 304 stainless steel using single and double femtosecond laser pulses. By adjusting polarization, fluence, and inter‐pulse delay, 1D and 2D nanostructures are formed. Enhanced hydrophobicity and dense surface‐enhanced Raman spectroscopy hotspots enable analyte detection down to 10−10 M with good ...
Balaji Baskar   +3 more
wiley   +1 more source

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht   +5 more
wiley   +1 more source

Effectiveness of BNT162b2 COVID-19 primary series vaccination in children aged 5–17 years in the United States: a cohort study

open access: yesBMC Pediatrics
Background COVID-19 vaccines are authorized for use in children in the United States; real-world assessment of vaccine effectiveness in children is needed. This study’s objective was to estimate the effectiveness of receiving a complete primary series of
Rachel P. Ogilvie   +28 more
doaj   +1 more source

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