Results 171 to 180 of about 731,751 (310)

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling in Regulatory Science: An Update From the U.S. Food and Drug Administration's Office of Clinical Pharmacology.

Journal of Pharmacy and Science, 2019
Manuela Grimstein, Yuching Yang, Xinyuan Zhang, J. Grillo, Shiew-Mei Huang, I. Zineh, Yaning Wang   +6 more
semanticscholar   +1 more source

Additively Manufactured Diamond for Energy Scavenging and Wireless Power Transfer in Implantable Devices

Advanced Functional Materials, EarlyView.
Additive manufacturing is expanding beyond mechanical prosthetics into microelectronic implants. This work presents a diamond‐titanium hybrid that enables wireless power transfer, localized heating, and flow sensing. The use of additive manufacturing combined with the biocompatibility of the diamond‐titanium hybrid material paves the way toward new ...
Joshua Zarins, Daniel De Maria, Alan Jones, Deepak Sharma, Amir Ebrahimi, Zhangyu Xu, Omid Kavehei, Peter C. Sherrell, Kate Fox, Arman Ahnood   +9 more
wiley   +1 more source

Interlaboratory Evaluation of the U.S. Food and Drug Administration Escherichia coli Identification Microarray for Profiling Shiga Toxin–Producing Escherichia coli

, 2018
Isha R. Patel, Jayanthi Gangiredla, David W. Lacher, Mark K. Mammel, Lori K. Bagi, Gian Marco Baranzoni, Pina M. Fratamico, Elizabeth L. Roberts, Chitrita DebRoy, Rebecca L. Lindsey, Devon Stoneburg, Haley Martin, P. B. Smith, Nancy Strockbine, Christopher A. Elkins, Flemming Scheutz, Peter Feng   +16 more
openalex   +2 more sources

Combined Pediatric and Adult Trials Submitted to the US Food and Drug Administration 2012–2018

Clinical pharmacology and therapy, 2020
Irin Tanaudommongkon, Shogo John Miyagi, D. Green, Janelle M. Burnham, J. Anker, Kyunghun Park, Johanna Wu, S. McCune, L. Yao, G. Burckart   +9 more
semanticscholar   +1 more source

Bio‐Responsive Hydrogel for Targeted on‐Demand Release of a Phage Cocktail for Treatment of Pseudomonas aeruginosa Infection

Advanced Functional Materials, EarlyView.
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao, Anna Hu, Elnaz Bavel, Chien‐Hsun Yu, Sixuan Zhang, Vera Maria Kissling, Zhihao Li, Thomas Fintan Moriaty, Katharina Maniura‐Weber, Qun Ren   +9 more
wiley   +1 more source

Qualitative study of oncologists' perceptions on the US Food and Drug Administration approval status and clinical practice guidelines and their impact on local practice patterns in India. [PDF]

BMJ Oncol
Datta S, Sharma V, Mukherjee A, Agrawal S, Sirohi B, Gyawali B.   +5 more
europepmc   +1 more source

Bicontinuous Microarchitected Scaffolds Provide Topographic Cues That Govern Neuronal Behavior and Maturation

Advanced Functional Materials, EarlyView.
A scalable biomimetic platform transforms bioinert poly(ethylene glycol) diacrylate into neuroinstructive matrices via integrating solvent transfer‐induced phase separation, microfluidics, and 3D bioprinting. Bicontinuous, hyperbolically curved microporous networks embedded within a fibrous construct elicit rapid adhesion, robust proliferation, and ...
Prince D. Okoro, Kevin Dalsania, Shiril B. Iragavarapu, Benjamin Dela Cruz, Aihik Banerjee, Merve Basaranbilek, Martin F. Haase, Bahman Anvari, Iman Noshadi   +8 more
wiley   +1 more source

A significant number of pediatric inflammatory bowel disease patients are exposed to a medication not approved by the Food and Drug Administration for pediatric use. [PDF]

J Pediatr Gastroenterol Nutr
Rusch C, Perkins AJ, Steiner SJ, ImproveCareNow Pediatric IBD Learning Health System.   +3 more
europepmc   +1 more source

The Synergy of Artificial Intelligence and 3D Bioprinting: Unlocking New Frontiers in Precision and Tissue Fabrication

Advanced Functional Materials, EarlyView.
Advances in integrating artificial intelligence into 3D bioprinting are systematically reviewed here. Machine learning, computer vision, robotics, natural language processing, and expert systems are examined for their roles in optimizing bioprinting parameters, real‐time monitoring, quality control, and predictive maintenance.
Joao Vitor Silva Robazzi, Irem Deniz Derman, Deepak Gupta, Logan Haugh, Yogendra Pratap Singh, Vaibhav Pal, Yasar Ozer Yilmaz, Suihong Liu, Andre Luis Dias, Rogerio Andrade Flauzino, Ibrahim Tarik Ozbolat   +10 more
wiley   +1 more source