Results 11 to 20 of about 3,258,233 (341)

Interventions and compliance

Journal of Agriculture, Food Systems, and Community Development, 2020
Preventing the spread of infectious disease relies heavily upon the development and implementation of public health interventions. The requisite debate over the effectiveness of these interventions is accom­panied by discussions about which, if any ...
Girvin Liggans, Devin Dutilly, Komita Carrington-Liggans, Mary Cartagena, Charles Idjagboro, Laurie Williams, Glenda Lewis, Mia Russell, Veronica Moore, Robert Sudler   +9 more
doaj   +1 more source

Is the Food and Drug Administration Safe and Effective? [PDF]

Journal of Economic Perspectives, 2007
In the United States, the Food and Drug Administration (FDA) provides public oversight of the safety and efficacy of drugs; medical devices; biologics like vaccines and blood products; cosmetics; radiation-emitting electronic products; veterinary products; and all foods, except meat and poultry (which are regulated by the Department of Agriculture ...
Tomas J. Philipson, Eric Sun
openaire   +6 more sources

BRAF and MEK inhibitors differentially affect nivolumab-induced T cell activation by modulating the TCR and AKT signaling pathways

OncoImmunology, 2019
Immune checkpoint inhibitors (ICIs) such as the anti-PD-1 antibody Nivolumab, achieve remarkable clinical efficacy in patients with late stage cancers. However, only a small subset of patients benefit from this therapy.
Peng Yue, Taylor Harper, Silvia M. Bacot, Monica Chowdhury, Shiowjen Lee, Adovi Akue, Mark A. Kukuruga, Tao Wang, Gerald M. Feldman   +8 more
doaj   +1 more source

Atezolizumab potentiates Tcell-mediated cytotoxicity and coordinates with FAK to suppress cell invasion and motility in PD-L1+ triple negative breast cancer cells

OncoImmunology, 2019
Immune check point inhibitors targeting programmed cell death protein-1 (PD-1) and its ligand (PD-L1) have shown clinical success in treatment of human malignancies.
Nishant Mohan, Salman Hosain, Jun Zhao, Yi Shen, Xiao Luo, Jiangsong Jiang, Yukinori Endo, Wen Jin Wu   +7 more
doaj   +1 more source

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Particle and Fibre Toxicology, 2017
Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (
James L. Weaver, Grainne A. Tobin, Taylor Ingle, Simona Bancos, David Stevens, Rodney Rouse, Kristina E. Howard, David Goodwin, Alan Knapton, Xiaohong Li, Katherine Shea, Sharron Stewart, Lin Xu, Peter L. Goering, Qin Zhang, Paul C. Howard, Jessie Collins, Saeed Khan, Kidon Sung, Katherine M. Tyner   +19 more
doaj   +1 more source

Health Disparities in Calorie Knowledge and Confidence Among the U.S. Adult Population

Journal of Primary Care & Community Health, 2021
Purpose Obesity prevalence has reached an all-time high in the US, affecting >40% of the population. This study’s objective was to evaluate associations between demographics and self-reported calorie knowledge and self-perceived confidence in calorie ...
Amy M. Lando, Martine S. Ferguson, Linda Verrill, Fanfan Wu, Olivia E. Jones-Dominic, Cecile Punzalan, Beverly J. Wolpert   +6 more
doaj   +1 more source

Modulation of innate immune mechanisms to enhance vaccine induced immunity: Role of co-inhibitory molecules

Frontiers in Immunology, 2016
No licensed human vaccines are currently available against any parasitic disease including leishmaniasis. Several anti-leishmanial vaccine formulations have been tested in various animal models including genetically modified live attenuated parasite ...
Sreenivas eGannavaram, Parna eBhattacharya, Nevien eIsmail, Amit eKaul, Rakesh eSingh, Hira eNakhasi   +5 more
doaj   +1 more source

Development of a custom-designed, pan genomic DNA microarray to characterize strain-level diversity among Cronobacter spp.

Frontiers in Pediatrics, 2015
Cronobacter species cause infections in all age groups; however neonates are at highest risk and remain the most susceptible age group for life-threatening invasive disease. The genus contains seven species: C. sakazakii, C. malonaticus, C. turicensis C.
Ben Davies Tall, Jayanthi eGangiredla, Gopal eGOPINATHRAO, Qiongqiong eYan, Hannah R Chase, B eLee, S eHwang, L eTrach, Eunbi ePark, Y eYoo, TaeJung eChung, Scott eJackson, Isha ePatel, Venugopal eSathyamoorthy, Monica ePava-Ripoll, Michael eKotewicz, Laurenda eCarter, C eIversen, Franco ePagotto, Roger eStephan, A eLehner, Seamus eFanning, Christopher eGrim   +22 more
doaj   +1 more source

Deep Learning Prediction of Adverse Drug Reactions Using Open TG-GATEs and FAERS Databases [PDF]

, 2020
With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to assess the possibility of adverse drug reactions or events (ADRs) in the course of drug discovery.
arxiv   +1 more source

Characterization of Vibrio parahaemolyticus clinical strains from Maryland (2012-2013) and comparisons to a locally and globally diverse V. parahaemolyticus strains by Whole-Genome Sequence Analysis

Frontiers in Microbiology, 2015
Vibrio parahaemolyticus is the leading cause of foodborne illnesses in the US associated with the consumption of raw shellfish. Previous population studies of V.
Julie eHaendiges, Ruth eTimme, Marc William Allard, Robert A Myers, Robert A Myers, Eric Wayne Brown, Narjol eGonzález-Escalona   +6 more
doaj   +1 more source