Results 261 to 270 of about 731,751 (310)

First, Do No Harm: Addressing AI's Challenges With Out‐of‐Distribution Data in Medicine

Clinical and Translational Science
Chu Weng, Wesley Lin, Sherry Dong, Qi Liu, Hanrui Zhang   +4 more
doaj   +1 more source

A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen‐Based Bioink for Skin Wound Healing Applied by a Handheld Dual‐Head Airbrush

Advanced Healthcare Materials, EarlyView.
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán, Daniel Nieto‐García, Carlos Chocarro‐Wrona, Juan de Vicente, Patricia Gálvez‐Martín, José Manuel Entrena, Elena López‐Ruiz, Juan Antonio Marchal   +7 more
wiley   +1 more source

Transparency of artificial intelligence/machine learning-enabled medical devices

npj Digital Medicine
Aubrey A. Shick, Christina M. Webber, Nooshin Kiarashi, Jessica P. Weinberg, Aneesh Deoras, Nicholas Petrick, Anindita Saha, Matthew C. Diamond   +7 more
doaj   +1 more source

Facile Deep Brain Electrode Coating with MXene for Improved Electrode Performance

Advanced Healthcare Materials, EarlyView.
Facile dip‐coating of commercial carbon fiber electrodes with Ti3C2Tx MXene improves electrical conductivity, reduces impedance, and enables single‐neuron recordings in the rat hippocampus over four weeks. The coating maintains biocompatibility, minimizes inflammation, and remains MRI‐compatible.
Laura Kondrataviciute, Taufik A. Valiante, Luka Milosevic, Lorraine V. Kalia, Dong Wook Kim, Suneil K. Kalia   +5 more
wiley   +1 more source

Specificity of Food and Drug Administration postmarketing requirements and associations with timely submissions and regulatory decisions for oncology accelerated approvals, 2011-2023: a cross-sectional analysis. [PDF]

BMJ Oncol
Kurian M, Ferrell WJ, Ulloa Perez E, Hubbard R, Joffe S, Mamtani R, Parikh RB, Lynch HF.   +7 more
europepmc   +1 more source

Possible Eye Disorders in Children Prenatally Exposed to Either Methadone or Buprenorphine in Comparison with Other Medications: An Examination of the Food and Drug Administration (FDA) Pharmacovigilance Database

Stefania Chiappini, Laura Orsolini, John Corkery, Amira Guirguis, Alessio Mosca, Davide Arillotta, Giovanni Martinotti, Fabrizio Schifano   +7 more
openalex   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

Trends in complexity of single-agent and combination therapies for solid tumor cancers approved by the US Food and Drug Administration. [PDF]

Oncologist
Chen EY, Rai M, Tadikonda Y, Roy P, Nollner DW, Chitkara A, Hamilton J, Thawani R.   +7 more
europepmc   +1 more source

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Impact of Global Enrollment on Race, Ethnicity, and Age Representation in Pivotal Gynecologic Cancer Trials Leading to US Food and Drug Administration Drug Approvals. [PDF]

JCO Glob Oncol
Khan MH, Ibanez KR, Bowen C, Donohue D, Oluloro A, Swisher EM, Lee JM.   +6 more
europepmc   +1 more source