Results 21 to 30 of about 687,018 (362)

Interventions and compliance

Journal of Agriculture, Food Systems, and Community Development, 2020
Preventing the spread of infectious disease relies heavily upon the development and implementation of public health interventions. The requisite debate over the effectiveness of these interventions is accom­panied by discussions about which, if any ...
Girvin Liggans, Devin Dutilly, Komita Carrington-Liggans, Mary Cartagena, Charles Idjagboro, Laurie Williams, Glenda Lewis, Mia Russell, Veronica Moore, Robert Sudler   +9 more
doaj   +1 more source

The role of PD-L1 expression as a predictive biomarker: an analysis of all US Food and Drug Administration (FDA) approvals of immune checkpoint inhibitors

Journal of Immunotherapy for Cancer, 2019
The development of immune checkpoint inhibitors has changed the treatment paradigm for advanced cancers across many tumor types. Despite encouraging and sometimes durable responses in a subset of patients, most patients do not respond.
A. Davis, V. Patel
semanticscholar   +1 more source

The FDA’s Diverse and Dynamic Activities in the Social and Behavioral Sciences: Advancing and Supporting Health Equity

Journal of Primary Care & Community Health, 2021
The U.S. encompasses a heterogenous mix of people and health disparities exist for various subpopulations, such as minorities, women, people with limited English proficiency, those with low socioeconomic status, and other underserved groups.
Christine Lee, Melanie J. McLean, Caroline J. Huang, Anh Nguyen Zarndt, Kathryn J. Aikin, Paula Rausch, Barbara R. Cohen, Janine Delahanty, Danielle M. Sholly, Wendy I. Slavit, Ewa D. Carlton   +10 more
doaj   +1 more source

Health Claims About Cannabidiol Products: A Retrospective Analysis of U.S. Food and Drug Administration Warning Letters from 2015 to 2019.

Cannabis and Cannabinoid Research, 2021
Background: Cannabidiol (CBD) products are increasingly available to consumers in the United States and are subject to regulation by the U.S. Food and Drug Administration (FDA).
Kimberly G. Wagoner, A. Lazard, E. Romero-Sandoval, B. Reboussin   +3 more
semanticscholar   +1 more source

Is the Food and Drug Administration Safe and Effective? [PDF]

Journal of Economic Perspectives, 2007
In the United States, the Food and Drug Administration (FDA) provides public oversight of the safety and efficacy of drugs; medical devices; biologics like vaccines and blood products; cosmetics; radiation-emitting electronic products; veterinary products; and all foods, except meat and poultry (which are regulated by the Department of Agriculture ...
Tomas J. Philipson, Eric Sun
openaire   +6 more sources

BRAF and MEK inhibitors differentially affect nivolumab-induced T cell activation by modulating the TCR and AKT signaling pathways

OncoImmunology, 2019
Immune checkpoint inhibitors (ICIs) such as the anti-PD-1 antibody Nivolumab, achieve remarkable clinical efficacy in patients with late stage cancers. However, only a small subset of patients benefit from this therapy.
Peng Yue, Taylor Harper, Silvia M. Bacot, Monica Chowdhury, Shiowjen Lee, Adovi Akue, Mark A. Kukuruga, Tao Wang, Gerald M. Feldman   +8 more
doaj   +1 more source

Health Disparities in Calorie Knowledge and Confidence Among the U.S. Adult Population

Journal of Primary Care & Community Health, 2021
Purpose Obesity prevalence has reached an all-time high in the US, affecting >40% of the population. This study’s objective was to evaluate associations between demographics and self-reported calorie knowledge and self-perceived confidence in calorie ...
Amy M. Lando, Martine S. Ferguson, Linda Verrill, Fanfan Wu, Olivia E. Jones-Dominic, Cecile Punzalan, Beverly J. Wolpert   +6 more
doaj   +1 more source

Ten‐Year Trends in Enrollment of Women and Minorities in Pivotal Trials Supporting Recent US Food and Drug Administration Approval of Novel Cardiometabolic Drugs

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020
Background In 1993, the US Food and Drug Administration established guidelines to increase diversity by sex and race/ethnicity of participants in clinical trials supporting novel drug approvals.
M. Khan, Izza Shahid, T. Siddiqi, Safi U. Khan, Haider J. Warraich, S. Greene, J. Butler, E. Michos   +7 more
semanticscholar   +1 more source

A COVID‐19‐ready public health surveillance system: The Food and Drug Administration's Sentinel System

Pharmacoepidemiology and Drug Safety, 2021
The US Food and Drug Administration's Sentinel System was established in 2009 to use routinely collected electronic health data for improving the national capability to assess post‐market medical product safety.
N. Cocoros, C. Fuller, S. Adimadhyam, R. Ball, Jeffrey S. Brown, G. D. Dal Pan, Sheryl A. Kluberg, V. Lo Re, J. Maro, M. Nguyen, Robert Orr, Dianne Paraoan, J. Perlin, R. Poland, Meighan Rogers Driscoll, K. Sands, S. Toh, W. K. Yih, R. Platt, Catherine Grace Sarah K. Wei Brian Silvia Danijela Corinne Corey Chai Dutcher Hua Kit Perez‐Vilar Stojanovic , Catherine Corey, Grace Chai, S. Dutcher, Wei Hua, Brian Kit, Silvia Perez-Vilar, D. Stojanovic, Corinne Woods   +27 more
semanticscholar   +1 more source

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Particle and Fibre Toxicology, 2017
Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (
James L. Weaver, Grainne A. Tobin, Taylor Ingle, Simona Bancos, David Stevens, Rodney Rouse, Kristina E. Howard, David Goodwin, Alan Knapton, Xiaohong Li, Katherine Shea, Sharron Stewart, Lin Xu, Peter L. Goering, Qin Zhang, Paul C. Howard, Jessie Collins, Saeed Khan, Kidon Sung, Katherine M. Tyner   +19 more
doaj   +1 more source